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Main Authors: Cortes-Gomez, Santiago, Raman, Naveen, Singh, Aarti, Wilder, Bryan
Format: Preprint
Published: 2024
Subjects:
Online Access:https://arxiv.org/abs/2410.11212
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author Cortes-Gomez, Santiago
Raman, Naveen
Singh, Aarti
Wilder, Bryan
author_facet Cortes-Gomez, Santiago
Raman, Naveen
Singh, Aarti
Wilder, Bryan
contents Randomized controlled trials (RCTs) can be used to generate guarantees on treatment effects. However, RCTs often spend unnecessary resources exploring sub-optimal treatments, which can reduce the power of treatment guarantees. To address these concerns, we develop a two-stage RCT where, first on a data-driven screening stage, we prune low-impact treatments, while in the second stage, we develop high probability lower bounds on the treatment effect. Unlike existing adaptive RCT frameworks, our method is simple enough to be implemented in scenarios with limited adaptivity. We derive optimal designs for two-stage RCTs and demonstrate how we can implement such designs through sample splitting. Empirically, we demonstrate that two-stage designs improve upon single-stage approaches, especially in scenarios where domain knowledge is available in the form of a prior. Our work is thus, a simple, yet effective, method to estimate high probablility certificates for high performant treatment effects on a RCT.
format Preprint
id arxiv_https___arxiv_org_abs_2410_11212
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Data-driven Design of Randomized Control Trials with Guaranteed Treatment Effects
Cortes-Gomez, Santiago
Raman, Naveen
Singh, Aarti
Wilder, Bryan
Computers and Society
Randomized controlled trials (RCTs) can be used to generate guarantees on treatment effects. However, RCTs often spend unnecessary resources exploring sub-optimal treatments, which can reduce the power of treatment guarantees. To address these concerns, we develop a two-stage RCT where, first on a data-driven screening stage, we prune low-impact treatments, while in the second stage, we develop high probability lower bounds on the treatment effect. Unlike existing adaptive RCT frameworks, our method is simple enough to be implemented in scenarios with limited adaptivity. We derive optimal designs for two-stage RCTs and demonstrate how we can implement such designs through sample splitting. Empirically, we demonstrate that two-stage designs improve upon single-stage approaches, especially in scenarios where domain knowledge is available in the form of a prior. Our work is thus, a simple, yet effective, method to estimate high probablility certificates for high performant treatment effects on a RCT.
title Data-driven Design of Randomized Control Trials with Guaranteed Treatment Effects
topic Computers and Society
url https://arxiv.org/abs/2410.11212