Synthetic Augmentation for Anatomical Landmark Localization using DDPMs

Fuente: arXiv
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Auteurs principaux: Hadzic, Arnela, Bogensperger, Lea, Joham, Simon Johannes, Urschler, Martin
Format: Preprint
Publié: 2024
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author Hadzic, Arnela
Bogensperger, Lea
Joham, Simon Johannes
Urschler, Martin
author_facet Hadzic, Arnela
Bogensperger, Lea
Joham, Simon Johannes
Urschler, Martin
contents Deep learning techniques for anatomical landmark localization (ALL) have shown great success, but their reliance on large annotated datasets remains a problem due to the tedious and costly nature of medical data acquisition and annotation. While traditional data augmentation, variational autoencoders (VAEs), and generative adversarial networks (GANs) have already been used to synthetically expand medical datasets, diffusion-based generative models have recently started to gain attention for their ability to generate high-quality synthetic images. In this study, we explore the use of denoising diffusion probabilistic models (DDPMs) for generating medical images and their corresponding heatmaps of landmarks to enhance the training of a supervised deep learning model for ALL. Our novel approach involves a DDPM with a 2-channel input, incorporating both the original medical image and its heatmap of annotated landmarks. We also propose a novel way to assess the quality of the generated images using a Markov Random Field (MRF) model for landmark matching and a Statistical Shape Model (SSM) to check landmark plausibility, before we evaluate the DDPM-augmented dataset in the context of an ALL task involving hand X-Rays.
format Preprint
id arxiv_https___arxiv_org_abs_2410_12489
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Synthetic Augmentation for Anatomical Landmark Localization using DDPMs
Hadzic, Arnela
Bogensperger, Lea
Joham, Simon Johannes
Urschler, Martin
Computer Vision and Pattern Recognition
Deep learning techniques for anatomical landmark localization (ALL) have shown great success, but their reliance on large annotated datasets remains a problem due to the tedious and costly nature of medical data acquisition and annotation. While traditional data augmentation, variational autoencoders (VAEs), and generative adversarial networks (GANs) have already been used to synthetically expand medical datasets, diffusion-based generative models have recently started to gain attention for their ability to generate high-quality synthetic images. In this study, we explore the use of denoising diffusion probabilistic models (DDPMs) for generating medical images and their corresponding heatmaps of landmarks to enhance the training of a supervised deep learning model for ALL. Our novel approach involves a DDPM with a 2-channel input, incorporating both the original medical image and its heatmap of annotated landmarks. We also propose a novel way to assess the quality of the generated images using a Markov Random Field (MRF) model for landmark matching and a Statistical Shape Model (SSM) to check landmark plausibility, before we evaluate the DDPM-augmented dataset in the context of an ALL task involving hand X-Rays.
title Synthetic Augmentation for Anatomical Landmark Localization using DDPMs
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2410.12489