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Main Authors: Fritsak, Maksym, Gabryś, Hubert S., Mohan, Preethi, Guckenberger, Matthias, Tanadini-Lang, Stephanie
Format: Preprint
Published: 2024
Subjects:
Online Access:https://arxiv.org/abs/2410.13348
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author Fritsak, Maksym
Gabryś, Hubert S.
Mohan, Preethi
Guckenberger, Matthias
Tanadini-Lang, Stephanie
author_facet Fritsak, Maksym
Gabryś, Hubert S.
Mohan, Preethi
Guckenberger, Matthias
Tanadini-Lang, Stephanie
contents The Standardized Uptake Value (SUV) is a critical metric in positron emission tomography (PET) imaging, used to assess metabolic activity. However, calculating SUV from DICOM files presents challenges due to vendor-specific DICOM attributes and variations in the encoding of radiotracer accumulation times. This technical note introduces a robust, vendor-specific SUV calculation strategy that addresses inconsistencies in current methodologies. We also integrate this strategy into an open-source software solution, Z-Rad, capable of converting raw PET DICOM data into body-weight normalized SUV NIfTI files. Our SUV calculation strategy was developed by reviewing DICOM conformance statements from GE, Philips, and Siemens. Validation was conducted using real-world PET datasets, and the proposed strategy was compared to existing software solutions. Our SUV calculation approach demonstrated improved accuracy, particularly in resolving time-related discrepancies in the studied data. Our analysis also identified inconsistencies in the SUV calculation methods used by popular commercial and open-source software solutions, which do not fully account for vendor-specific DICOM attributes and PET image acquisition times. These limitations resulted in errors in SUV estimation reaching 33\% when comparing our strategy to studied software. The proposed vendor-specific SUV calculation strategy significantly enhances accuracy in PET imaging by addressing key inconsistencies caused by variations in DICOM attributes and image acquisition times across different vendors. This method effectively reduces SUV calculation errors and has been integrated into an open-source software, Z-Rad.
format Preprint
id arxiv_https___arxiv_org_abs_2410_13348
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Technical Note: Vendor-Specific Approach for Standardized Uptake Value Calculation
Fritsak, Maksym
Gabryś, Hubert S.
Mohan, Preethi
Guckenberger, Matthias
Tanadini-Lang, Stephanie
Medical Physics
The Standardized Uptake Value (SUV) is a critical metric in positron emission tomography (PET) imaging, used to assess metabolic activity. However, calculating SUV from DICOM files presents challenges due to vendor-specific DICOM attributes and variations in the encoding of radiotracer accumulation times. This technical note introduces a robust, vendor-specific SUV calculation strategy that addresses inconsistencies in current methodologies. We also integrate this strategy into an open-source software solution, Z-Rad, capable of converting raw PET DICOM data into body-weight normalized SUV NIfTI files. Our SUV calculation strategy was developed by reviewing DICOM conformance statements from GE, Philips, and Siemens. Validation was conducted using real-world PET datasets, and the proposed strategy was compared to existing software solutions. Our SUV calculation approach demonstrated improved accuracy, particularly in resolving time-related discrepancies in the studied data. Our analysis also identified inconsistencies in the SUV calculation methods used by popular commercial and open-source software solutions, which do not fully account for vendor-specific DICOM attributes and PET image acquisition times. These limitations resulted in errors in SUV estimation reaching 33\% when comparing our strategy to studied software. The proposed vendor-specific SUV calculation strategy significantly enhances accuracy in PET imaging by addressing key inconsistencies caused by variations in DICOM attributes and image acquisition times across different vendors. This method effectively reduces SUV calculation errors and has been integrated into an open-source software, Z-Rad.
title Technical Note: Vendor-Specific Approach for Standardized Uptake Value Calculation
topic Medical Physics
url https://arxiv.org/abs/2410.13348