Spatial Proportional Hazards Model with Differential Regularization

Fuente: arXiv
Saved in:
Bibliographic Details
Main Authors: Tedesco, Lorenzo, Finazzi, Francesco
Format: Preprint
Published: 2024
Subjects:
Online Access:
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1866908834794045440
author Tedesco, Lorenzo
Finazzi, Francesco
author_facet Tedesco, Lorenzo
Finazzi, Francesco
contents The Proportional Hazards (PH) model is one of the most widely used models in survival analysis, typically assuming a log-linear relationship between covariates and the hazard function. However, in the context of spatial survival data, where the time-to-event variable is associated with a spatial location within a given domain, this assumption is often unrealistic in capturing spatial effects. Thus, this paper proposes modeling the location effect through a nonparametric function of spatial location. The function is approximated using finite element methods on a triangulated mesh to accommodate irregular domains. Estimation is carried out within the classical partial likelihood framework, with smoothness of the spatial effect enforced through differential penalization. Using sieve methods, we establish the consistency and asymptotic normality of the parametric component. Simulations and two empirical applications demonstrate superior performance compared to existing approaches.
format Preprint
id arxiv_https___arxiv_org_abs_2410_13420
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Spatial Proportional Hazards Model with Differential Regularization
Tedesco, Lorenzo
Finazzi, Francesco
Methodology
Statistics Theory
62N02, 62G05
The Proportional Hazards (PH) model is one of the most widely used models in survival analysis, typically assuming a log-linear relationship between covariates and the hazard function. However, in the context of spatial survival data, where the time-to-event variable is associated with a spatial location within a given domain, this assumption is often unrealistic in capturing spatial effects. Thus, this paper proposes modeling the location effect through a nonparametric function of spatial location. The function is approximated using finite element methods on a triangulated mesh to accommodate irregular domains. Estimation is carried out within the classical partial likelihood framework, with smoothness of the spatial effect enforced through differential penalization. Using sieve methods, we establish the consistency and asymptotic normality of the parametric component. Simulations and two empirical applications demonstrate superior performance compared to existing approaches.
title Spatial Proportional Hazards Model with Differential Regularization
topic Methodology
Statistics Theory
62N02, 62G05
url https://arxiv.org/abs/2410.13420