MedDiff-FM: A Diffusion-based Foundation Model for Versatile Medical Image Applications

Fuente: arXiv
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Hauptverfasser: Yu, Yongrui, Gu, Yannian, Zhang, Shaoting, Zhang, Xiaofan
Format: Preprint
Veröffentlicht: 2024
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author Yu, Yongrui
Gu, Yannian
Zhang, Shaoting
Zhang, Xiaofan
author_facet Yu, Yongrui
Gu, Yannian
Zhang, Shaoting
Zhang, Xiaofan
contents Diffusion models have achieved significant success in both natural image and medical image domains, encompassing a wide range of applications. Previous investigations in medical images have often been constrained to specific anatomical regions, particular applications, and limited datasets, resulting in isolated diffusion models. This paper introduces a diffusion-based foundation model to address a diverse range of medical image tasks, namely MedDiff-FM. MedDiff-FM leverages 3D CT images from multiple publicly available datasets, covering anatomical regions from head to abdomen, to pre-train a diffusion foundation model, and explores the capabilities of the diffusion foundation model across a variety of application scenarios. The diffusion foundation model handles multi-level integrated image processing both at the image-level and patch-level, utilizes position embedding to establish multi-level spatial relationships, and leverages region classes and anatomical structures to capture certain anatomical regions. MedDiff-FM manages several downstream tasks seamlessly, including image denoising, anomaly detection, and image synthesis. MedDiff-FM is also capable of performing super-resolution, lesion generation, and lesion inpainting by rapidly fine-tuning the diffusion foundation model using ControlNet with task-specific conditions. The experimental results demonstrate the effectiveness of MedDiff-FM in addressing diverse downstream medical image tasks.
format Preprint
id arxiv_https___arxiv_org_abs_2410_15432
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle MedDiff-FM: A Diffusion-based Foundation Model for Versatile Medical Image Applications
Yu, Yongrui
Gu, Yannian
Zhang, Shaoting
Zhang, Xiaofan
Computer Vision and Pattern Recognition
Diffusion models have achieved significant success in both natural image and medical image domains, encompassing a wide range of applications. Previous investigations in medical images have often been constrained to specific anatomical regions, particular applications, and limited datasets, resulting in isolated diffusion models. This paper introduces a diffusion-based foundation model to address a diverse range of medical image tasks, namely MedDiff-FM. MedDiff-FM leverages 3D CT images from multiple publicly available datasets, covering anatomical regions from head to abdomen, to pre-train a diffusion foundation model, and explores the capabilities of the diffusion foundation model across a variety of application scenarios. The diffusion foundation model handles multi-level integrated image processing both at the image-level and patch-level, utilizes position embedding to establish multi-level spatial relationships, and leverages region classes and anatomical structures to capture certain anatomical regions. MedDiff-FM manages several downstream tasks seamlessly, including image denoising, anomaly detection, and image synthesis. MedDiff-FM is also capable of performing super-resolution, lesion generation, and lesion inpainting by rapidly fine-tuning the diffusion foundation model using ControlNet with task-specific conditions. The experimental results demonstrate the effectiveness of MedDiff-FM in addressing diverse downstream medical image tasks.
title MedDiff-FM: A Diffusion-based Foundation Model for Versatile Medical Image Applications
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2410.15432