Federated Causal Inference: Multi-Study ATE Estimation beyond Meta-Analysis

Fuente: arXiv
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Autores principales: Khellaf, Rémi, Bellet, Aurélien, Josse, Julie
Formato: Preprint
Publicado: 2024
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author Khellaf, Rémi
Bellet, Aurélien
Josse, Julie
author_facet Khellaf, Rémi
Bellet, Aurélien
Josse, Julie
contents We study Federated Causal Inference, an approach to estimate treatment effects from decentralized data across centers. We compare three classes of Average Treatment Effect (ATE) estimators derived from the Plug-in G-Formula, ranging from simple meta-analysis to one-shot and multi-shot federated learning, the latter leveraging the full data to learn the outcome model (albeit requiring more communication). Focusing on Randomized Controlled Trials (RCTs), we derive the asymptotic variance of these estimators for linear models. Our results provide practical guidance on selecting the appropriate estimator for various scenarios, including heterogeneity in sample sizes, covariate distributions, treatment assignment schemes, and center effects. We validate these findings with a simulation study.
format Preprint
id arxiv_https___arxiv_org_abs_2410_16870
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Federated Causal Inference: Multi-Study ATE Estimation beyond Meta-Analysis
Khellaf, Rémi
Bellet, Aurélien
Josse, Julie
Machine Learning
Statistics Theory
We study Federated Causal Inference, an approach to estimate treatment effects from decentralized data across centers. We compare three classes of Average Treatment Effect (ATE) estimators derived from the Plug-in G-Formula, ranging from simple meta-analysis to one-shot and multi-shot federated learning, the latter leveraging the full data to learn the outcome model (albeit requiring more communication). Focusing on Randomized Controlled Trials (RCTs), we derive the asymptotic variance of these estimators for linear models. Our results provide practical guidance on selecting the appropriate estimator for various scenarios, including heterogeneity in sample sizes, covariate distributions, treatment assignment schemes, and center effects. We validate these findings with a simulation study.
title Federated Causal Inference: Multi-Study ATE Estimation beyond Meta-Analysis
topic Machine Learning
Statistics Theory
url https://arxiv.org/abs/2410.16870