Binding memory of liquid molecules
Fuente:
arXiv
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| Autores principales: | , , , , , |
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| Formato: | Preprint |
| Publicado: |
2024
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| Materias: | |
| Acceso en línea: | |
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| _version_ | 1866929558510370816 |
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| author | Qin, Shiyi Yang, Zhi Liu, Huimin Wang, Xiaoli Hou, Shangguo Huang, Kai |
| author_facet | Qin, Shiyi Yang, Zhi Liu, Huimin Wang, Xiaoli Hou, Shangguo Huang, Kai |
| contents | Understanding the binding dynamics of liquid molecules is of fundamental importance in physical and life sciences. However, nanoscale fast dynamics pose great challenges for experimental characterization. Conventionally, the binding dynamics have been assumed to be memoryless. Here, we integrate large scale computer simulation, scaling theory, and real-time single particle tracking microscopy with high spatiotemporal precision to unveil a universal memory effect in the binding dynamics of liquid molecules. This binding memory can be quantified by a binding time autocorrelation function, whose power-law decay depends not only on the binding affinity, but also on the topological and materials properties of the surrounding environment. Context-dependent biomolecular binding memory is likely exploited by biological systems to regulate biochemical reactions and biophysical processes. Deciphering this binding memory offers a novel strategy to probe complex biological systems and advanced soft materials. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2410_19634 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | Binding memory of liquid molecules Qin, Shiyi Yang, Zhi Liu, Huimin Wang, Xiaoli Hou, Shangguo Huang, Kai Chemical Physics Soft Condensed Matter Biological Physics Understanding the binding dynamics of liquid molecules is of fundamental importance in physical and life sciences. However, nanoscale fast dynamics pose great challenges for experimental characterization. Conventionally, the binding dynamics have been assumed to be memoryless. Here, we integrate large scale computer simulation, scaling theory, and real-time single particle tracking microscopy with high spatiotemporal precision to unveil a universal memory effect in the binding dynamics of liquid molecules. This binding memory can be quantified by a binding time autocorrelation function, whose power-law decay depends not only on the binding affinity, but also on the topological and materials properties of the surrounding environment. Context-dependent biomolecular binding memory is likely exploited by biological systems to regulate biochemical reactions and biophysical processes. Deciphering this binding memory offers a novel strategy to probe complex biological systems and advanced soft materials. |
| title | Binding memory of liquid molecules |
| topic | Chemical Physics Soft Condensed Matter Biological Physics |
| url | https://arxiv.org/abs/2410.19634 |