Generative AI in Health Economics and Outcomes Research: A Taxonomy of Key Definitions and Emerging Applications, an ISPOR Working Group Report

Fuente: arXiv
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Autores principales: Fleurence, Rachael, Wang, Xiaoyan, Bian, Jiang, Higashi, Mitchell K., Ayer, Turgay, Xu, Hua, Dawoud, Dalia, Chhatwal, Jagpreet
Formato: Preprint
Publicado: 2024
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author Fleurence, Rachael
Wang, Xiaoyan
Bian, Jiang
Higashi, Mitchell K.
Ayer, Turgay
Xu, Hua
Dawoud, Dalia
Chhatwal, Jagpreet
author_facet Fleurence, Rachael
Wang, Xiaoyan
Bian, Jiang
Higashi, Mitchell K.
Ayer, Turgay
Xu, Hua
Dawoud, Dalia
Chhatwal, Jagpreet
contents Objective: This article offers a taxonomy of generative artificial intelligence (AI) for health economics and outcomes research (HEOR), explores its emerging applications, and outlines methods to enhance the accuracy and reliability of AI-generated outputs. Methods: The review defines foundational generative AI concepts and highlights current HEOR applications, including systematic literature reviews, health economic modeling, real-world evidence generation, and dossier development. Approaches such as prompt engineering (zero-shot, few-shot, chain-of-thought, persona pattern prompting), retrieval-augmented generation, model fine-tuning, and the use of domain-specific models are introduced to improve AI accuracy and reliability. Results: Generative AI shows significant potential in HEOR, enhancing efficiency, productivity, and offering novel solutions to complex challenges. Foundation models are promising in automating complex tasks, though challenges remain in scientific reliability, bias, interpretability, and workflow integration. The article discusses strategies to improve the accuracy of these AI tools. Conclusion: Generative AI could transform HEOR by increasing efficiency and accuracy across various applications. However, its full potential can only be realized by building HEOR expertise and addressing the limitations of current AI technologies. As AI evolves, ongoing research and innovation will shape its future role in the field.
format Preprint
id arxiv_https___arxiv_org_abs_2410_20204
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Generative AI in Health Economics and Outcomes Research: A Taxonomy of Key Definitions and Emerging Applications, an ISPOR Working Group Report
Fleurence, Rachael
Wang, Xiaoyan
Bian, Jiang
Higashi, Mitchell K.
Ayer, Turgay
Xu, Hua
Dawoud, Dalia
Chhatwal, Jagpreet
Machine Learning
Artificial Intelligence
Computers and Society
Objective: This article offers a taxonomy of generative artificial intelligence (AI) for health economics and outcomes research (HEOR), explores its emerging applications, and outlines methods to enhance the accuracy and reliability of AI-generated outputs. Methods: The review defines foundational generative AI concepts and highlights current HEOR applications, including systematic literature reviews, health economic modeling, real-world evidence generation, and dossier development. Approaches such as prompt engineering (zero-shot, few-shot, chain-of-thought, persona pattern prompting), retrieval-augmented generation, model fine-tuning, and the use of domain-specific models are introduced to improve AI accuracy and reliability. Results: Generative AI shows significant potential in HEOR, enhancing efficiency, productivity, and offering novel solutions to complex challenges. Foundation models are promising in automating complex tasks, though challenges remain in scientific reliability, bias, interpretability, and workflow integration. The article discusses strategies to improve the accuracy of these AI tools. Conclusion: Generative AI could transform HEOR by increasing efficiency and accuracy across various applications. However, its full potential can only be realized by building HEOR expertise and addressing the limitations of current AI technologies. As AI evolves, ongoing research and innovation will shape its future role in the field.
title Generative AI in Health Economics and Outcomes Research: A Taxonomy of Key Definitions and Emerging Applications, an ISPOR Working Group Report
topic Machine Learning
Artificial Intelligence
Computers and Society
url https://arxiv.org/abs/2410.20204