Enhancing Osteoporosis Detection: An Explainable Multi-Modal Learning Framework with Feature Fusion and Variable Clustering

Fuente: arXiv
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Main Authors: Chagahi, Mehdi Hosseini, Dashtaki, Saeed Mohammadi, Delfan, Niloufar, Mohammadi, Nadia, Pouria, Farshid Rostami, Moshiri, Behzad, Piran, Md. Jalil, Faust, Oliver
Format: Preprint
Published: 2024
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author Chagahi, Mehdi Hosseini
Dashtaki, Saeed Mohammadi
Delfan, Niloufar
Mohammadi, Nadia
Pouria, Farshid Rostami
Moshiri, Behzad
Piran, Md. Jalil
Faust, Oliver
author_facet Chagahi, Mehdi Hosseini
Dashtaki, Saeed Mohammadi
Delfan, Niloufar
Mohammadi, Nadia
Pouria, Farshid Rostami
Moshiri, Behzad
Piran, Md. Jalil
Faust, Oliver
contents Osteoporosis is a common condition that increases fracture risk, especially in older adults. Early diagnosis is vital for preventing fractures, reducing treatment costs, and preserving mobility. However, healthcare providers face challenges like limited labeled data and difficulties in processing medical images. This study presents a novel multi-modal learning framework that integrates clinical and imaging data to improve diagnostic accuracy and model interpretability. The model utilizes three pre-trained networks-VGG19, InceptionV3, and ResNet50-to extract deep features from X-ray images. These features are transformed using PCA to reduce dimensionality and focus on the most relevant components. A clustering-based selection process identifies the most representative components, which are then combined with preprocessed clinical data and processed through a fully connected network (FCN) for final classification. A feature importance plot highlights key variables, showing that Medical History, BMI, and Height were the main contributors, emphasizing the significance of patient-specific data. While imaging features were valuable, they had lower importance, indicating that clinical data are crucial for accurate predictions. This framework promotes precise and interpretable predictions, enhancing transparency and building trust in AI-driven diagnoses for clinical integration.
format Preprint
id arxiv_https___arxiv_org_abs_2411_00916
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Enhancing Osteoporosis Detection: An Explainable Multi-Modal Learning Framework with Feature Fusion and Variable Clustering
Chagahi, Mehdi Hosseini
Dashtaki, Saeed Mohammadi
Delfan, Niloufar
Mohammadi, Nadia
Pouria, Farshid Rostami
Moshiri, Behzad
Piran, Md. Jalil
Faust, Oliver
Computer Vision and Pattern Recognition
Artificial Intelligence
Osteoporosis is a common condition that increases fracture risk, especially in older adults. Early diagnosis is vital for preventing fractures, reducing treatment costs, and preserving mobility. However, healthcare providers face challenges like limited labeled data and difficulties in processing medical images. This study presents a novel multi-modal learning framework that integrates clinical and imaging data to improve diagnostic accuracy and model interpretability. The model utilizes three pre-trained networks-VGG19, InceptionV3, and ResNet50-to extract deep features from X-ray images. These features are transformed using PCA to reduce dimensionality and focus on the most relevant components. A clustering-based selection process identifies the most representative components, which are then combined with preprocessed clinical data and processed through a fully connected network (FCN) for final classification. A feature importance plot highlights key variables, showing that Medical History, BMI, and Height were the main contributors, emphasizing the significance of patient-specific data. While imaging features were valuable, they had lower importance, indicating that clinical data are crucial for accurate predictions. This framework promotes precise and interpretable predictions, enhancing transparency and building trust in AI-driven diagnoses for clinical integration.
title Enhancing Osteoporosis Detection: An Explainable Multi-Modal Learning Framework with Feature Fusion and Variable Clustering
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2411.00916