Game-Theoretic Defenses for Robust Conformal Prediction Against Adversarial Attacks in Medical Imaging

Fuente: arXiv
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Autores principales: Luo, Rui, Bao, Jie, Zhou, Zhixin, Dang, Chuangyin
Formato: Preprint
Publicado: 2024
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author Luo, Rui
Bao, Jie
Zhou, Zhixin
Dang, Chuangyin
author_facet Luo, Rui
Bao, Jie
Zhou, Zhixin
Dang, Chuangyin
contents Adversarial attacks pose significant threats to the reliability and safety of deep learning models, especially in critical domains such as medical imaging. This paper introduces a novel framework that integrates conformal prediction with game-theoretic defensive strategies to enhance model robustness against both known and unknown adversarial perturbations. We address three primary research questions: constructing valid and efficient conformal prediction sets under known attacks (RQ1), ensuring coverage under unknown attacks through conservative thresholding (RQ2), and determining optimal defensive strategies within a zero-sum game framework (RQ3). Our methodology involves training specialized defensive models against specific attack types and employing maximum and minimum classifiers to aggregate defenses effectively. Extensive experiments conducted on the MedMNIST datasets, including PathMNIST, OrganAMNIST, and TissueMNIST, demonstrate that our approach maintains high coverage guarantees while minimizing prediction set sizes. The game-theoretic analysis reveals that the optimal defensive strategy often converges to a singular robust model, outperforming uniform and simple strategies across all evaluated datasets. This work advances the state-of-the-art in uncertainty quantification and adversarial robustness, providing a reliable mechanism for deploying deep learning models in adversarial environments.
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id arxiv_https___arxiv_org_abs_2411_04376
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publishDate 2024
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spellingShingle Game-Theoretic Defenses for Robust Conformal Prediction Against Adversarial Attacks in Medical Imaging
Luo, Rui
Bao, Jie
Zhou, Zhixin
Dang, Chuangyin
Machine Learning
Cryptography and Security
Image and Video Processing
Adversarial attacks pose significant threats to the reliability and safety of deep learning models, especially in critical domains such as medical imaging. This paper introduces a novel framework that integrates conformal prediction with game-theoretic defensive strategies to enhance model robustness against both known and unknown adversarial perturbations. We address three primary research questions: constructing valid and efficient conformal prediction sets under known attacks (RQ1), ensuring coverage under unknown attacks through conservative thresholding (RQ2), and determining optimal defensive strategies within a zero-sum game framework (RQ3). Our methodology involves training specialized defensive models against specific attack types and employing maximum and minimum classifiers to aggregate defenses effectively. Extensive experiments conducted on the MedMNIST datasets, including PathMNIST, OrganAMNIST, and TissueMNIST, demonstrate that our approach maintains high coverage guarantees while minimizing prediction set sizes. The game-theoretic analysis reveals that the optimal defensive strategy often converges to a singular robust model, outperforming uniform and simple strategies across all evaluated datasets. This work advances the state-of-the-art in uncertainty quantification and adversarial robustness, providing a reliable mechanism for deploying deep learning models in adversarial environments.
title Game-Theoretic Defenses for Robust Conformal Prediction Against Adversarial Attacks in Medical Imaging
topic Machine Learning
Cryptography and Security
Image and Video Processing
url https://arxiv.org/abs/2411.04376