Enhancing Trust in Clinically Significant Prostate Cancer Prediction with Multiple Magnetic Resonance Imaging Modalities

Fuente: arXiv
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Hauptverfasser: Ng, Benjamin, Tai, Chi-en Amy, Zeng, E. Zhixuan, Wong, Alexander
Format: Preprint
Veröffentlicht: 2024
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author Ng, Benjamin
Tai, Chi-en Amy
Zeng, E. Zhixuan
Wong, Alexander
author_facet Ng, Benjamin
Tai, Chi-en Amy
Zeng, E. Zhixuan
Wong, Alexander
contents In the United States, prostate cancer is the second leading cause of deaths in males with a predicted 35,250 deaths in 2024. However, most diagnoses are non-lethal and deemed clinically insignificant which means that the patient will likely not be impacted by the cancer over their lifetime. As a result, numerous research studies have explored the accuracy of predicting clinical significance of prostate cancer based on magnetic resonance imaging (MRI) modalities and deep neural networks. Despite their high performance, these models are not trusted by most clinical scientists as they are trained solely on a single modality whereas clinical scientists often use multiple magnetic resonance imaging modalities during their diagnosis. In this paper, we investigate combining multiple MRI modalities to train a deep learning model to enhance trust in the models for clinically significant prostate cancer prediction. The promising performance and proposed training pipeline showcase the benefits of incorporating multiple MRI modalities for enhanced trust and accuracy.
format Preprint
id arxiv_https___arxiv_org_abs_2411_04662
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Enhancing Trust in Clinically Significant Prostate Cancer Prediction with Multiple Magnetic Resonance Imaging Modalities
Ng, Benjamin
Tai, Chi-en Amy
Zeng, E. Zhixuan
Wong, Alexander
Machine Learning
In the United States, prostate cancer is the second leading cause of deaths in males with a predicted 35,250 deaths in 2024. However, most diagnoses are non-lethal and deemed clinically insignificant which means that the patient will likely not be impacted by the cancer over their lifetime. As a result, numerous research studies have explored the accuracy of predicting clinical significance of prostate cancer based on magnetic resonance imaging (MRI) modalities and deep neural networks. Despite their high performance, these models are not trusted by most clinical scientists as they are trained solely on a single modality whereas clinical scientists often use multiple magnetic resonance imaging modalities during their diagnosis. In this paper, we investigate combining multiple MRI modalities to train a deep learning model to enhance trust in the models for clinically significant prostate cancer prediction. The promising performance and proposed training pipeline showcase the benefits of incorporating multiple MRI modalities for enhanced trust and accuracy.
title Enhancing Trust in Clinically Significant Prostate Cancer Prediction with Multiple Magnetic Resonance Imaging Modalities
topic Machine Learning
url https://arxiv.org/abs/2411.04662