TourSynbio-Search: A Large Language Model Driven Agent Framework for Unified Search Method for Protein Engineering

Fuente: arXiv
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Main Authors: Liu, Yungeng, Chen, Zan, Wang, Yu Guang, Shen, Yiqing
Format: Preprint
Published: 2024
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author Liu, Yungeng
Chen, Zan
Wang, Yu Guang
Shen, Yiqing
author_facet Liu, Yungeng
Chen, Zan
Wang, Yu Guang
Shen, Yiqing
contents The exponential growth in protein-related databases and scientific literature, combined with increasing demands for efficient biological information retrieval, has created an urgent need for unified and accessible search methods in protein engineering research. We present TourSynbio-Search, a novel bioinformatics search agent framework powered by the TourSynbio-7B protein multimodal large language model (LLM), designed to address the growing challenges of information retrieval across rapidly expanding protein databases and corresponding online research literature. The agent's dual-module architecture consists of PaperSearch and ProteinSearch components, enabling comprehensive exploration of both scientific literature and protein data across multiple biological databases. At its core, TourSynbio-Search employs an intelligent agent system that interprets natural language queries, optimizes search parameters, and executes search operations across major platforms including UniProt, PDB, ArXiv, and BioRxiv. The agent's ability to process intuitive natural language queries reduces technical barriers, allowing researchers to efficiently access and analyze complex biological data without requiring extensive bioinformatics expertise. Through detailed case studies in literature retrieval and protein structure visualization, we demonstrate TourSynbio-Search's effectiveness in streamlining biological information retrieval and enhancing research productivity. This framework represents an advancement in bridging the accessibility gap between complex biological databases and researchers, potentially accelerating progress in protein engineering applications. Our codes are available at: https://github.com/tsynbio/Toursynbio-Search
format Preprint
id arxiv_https___arxiv_org_abs_2411_06024
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle TourSynbio-Search: A Large Language Model Driven Agent Framework for Unified Search Method for Protein Engineering
Liu, Yungeng
Chen, Zan
Wang, Yu Guang
Shen, Yiqing
Quantitative Methods
The exponential growth in protein-related databases and scientific literature, combined with increasing demands for efficient biological information retrieval, has created an urgent need for unified and accessible search methods in protein engineering research. We present TourSynbio-Search, a novel bioinformatics search agent framework powered by the TourSynbio-7B protein multimodal large language model (LLM), designed to address the growing challenges of information retrieval across rapidly expanding protein databases and corresponding online research literature. The agent's dual-module architecture consists of PaperSearch and ProteinSearch components, enabling comprehensive exploration of both scientific literature and protein data across multiple biological databases. At its core, TourSynbio-Search employs an intelligent agent system that interprets natural language queries, optimizes search parameters, and executes search operations across major platforms including UniProt, PDB, ArXiv, and BioRxiv. The agent's ability to process intuitive natural language queries reduces technical barriers, allowing researchers to efficiently access and analyze complex biological data without requiring extensive bioinformatics expertise. Through detailed case studies in literature retrieval and protein structure visualization, we demonstrate TourSynbio-Search's effectiveness in streamlining biological information retrieval and enhancing research productivity. This framework represents an advancement in bridging the accessibility gap between complex biological databases and researchers, potentially accelerating progress in protein engineering applications. Our codes are available at: https://github.com/tsynbio/Toursynbio-Search
title TourSynbio-Search: A Large Language Model Driven Agent Framework for Unified Search Method for Protein Engineering
topic Quantitative Methods
url https://arxiv.org/abs/2411.06024