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Main Authors: Arikan, Demir, Zhang, Peiyao, Sommersperger, Michael, Dehghani, Shervin, Esfandiari, Mojtaba, Taylor, Russel H., Nasseri, M. Ali, Gehlbach, Peter, Navab, Nassir, Iordachita, Iulian
Format: Preprint
Published: 2024
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Online Access:https://arxiv.org/abs/2411.06557
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author Arikan, Demir
Zhang, Peiyao
Sommersperger, Michael
Dehghani, Shervin
Esfandiari, Mojtaba
Taylor, Russel H.
Nasseri, M. Ali
Gehlbach, Peter
Navab, Nassir
Iordachita, Iulian
author_facet Arikan, Demir
Zhang, Peiyao
Sommersperger, Michael
Dehghani, Shervin
Esfandiari, Mojtaba
Taylor, Russel H.
Nasseri, M. Ali
Gehlbach, Peter
Navab, Nassir
Iordachita, Iulian
contents Robotic platforms provide consistent and precise tool positioning that significantly enhances retinal microsurgery. Integrating such systems with intraoperative optical coherence tomography (iOCT) enables image-guided robotic interventions, allowing autonomous performance of advanced treatments, such as injecting therapeutic agents into the subretinal space. However, tissue deformations due to tool-tissue interactions constitute a significant challenge in autonomous iOCT-guided robotic subretinal injections. Such interactions impact correct needle positioning and procedure outcomes. This paper presents a novel method for autonomous subretinal injection under iOCT guidance that considers tissue deformations during the insertion procedure. The technique is achieved through real-time segmentation and 3D reconstruction of the surgical scene from densely sampled iOCT B-scans, which we refer to as B${^5}$-scans. Using B${^5}$-scans we monitor the position of the instrument relative to a virtual target layer between the ILM and RPE. Our experiments on ex vivo porcine eyes demonstrate dynamic adjustment of the insertion depth and overall improved accuracy in needle positioning compared to prior autonomous insertion approaches. Compared to a 35% success rate in subretinal bleb generation with previous approaches, our method reliably created subretinal blebs in 90% our experiments.
format Preprint
id arxiv_https___arxiv_org_abs_2411_06557
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Real-time Deformation-aware Control for Autonomous Robotic Subretinal Injection under iOCT Guidance
Arikan, Demir
Zhang, Peiyao
Sommersperger, Michael
Dehghani, Shervin
Esfandiari, Mojtaba
Taylor, Russel H.
Nasseri, M. Ali
Gehlbach, Peter
Navab, Nassir
Iordachita, Iulian
Robotics
Robotic platforms provide consistent and precise tool positioning that significantly enhances retinal microsurgery. Integrating such systems with intraoperative optical coherence tomography (iOCT) enables image-guided robotic interventions, allowing autonomous performance of advanced treatments, such as injecting therapeutic agents into the subretinal space. However, tissue deformations due to tool-tissue interactions constitute a significant challenge in autonomous iOCT-guided robotic subretinal injections. Such interactions impact correct needle positioning and procedure outcomes. This paper presents a novel method for autonomous subretinal injection under iOCT guidance that considers tissue deformations during the insertion procedure. The technique is achieved through real-time segmentation and 3D reconstruction of the surgical scene from densely sampled iOCT B-scans, which we refer to as B${^5}$-scans. Using B${^5}$-scans we monitor the position of the instrument relative to a virtual target layer between the ILM and RPE. Our experiments on ex vivo porcine eyes demonstrate dynamic adjustment of the insertion depth and overall improved accuracy in needle positioning compared to prior autonomous insertion approaches. Compared to a 35% success rate in subretinal bleb generation with previous approaches, our method reliably created subretinal blebs in 90% our experiments.
title Real-time Deformation-aware Control for Autonomous Robotic Subretinal Injection under iOCT Guidance
topic Robotics
url https://arxiv.org/abs/2411.06557