How quantum computing can enhance biomarker discovery

Fuente: arXiv
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Main Authors: Flöther, Frederik F., Blankenberg, Daniel, Demidik, Maria, Jansen, Karl, Krishnakumar, Raga, Krishnakumar, Rajiv, Laanait, Nouamane, Parida, Laxmi, Saab, Carl, Utro, Filippo
Format: Preprint
Published: 2024
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author Flöther, Frederik F.
Blankenberg, Daniel
Demidik, Maria
Jansen, Karl
Krishnakumar, Raga
Krishnakumar, Rajiv
Laanait, Nouamane
Parida, Laxmi
Saab, Carl
Utro, Filippo
author_facet Flöther, Frederik F.
Blankenberg, Daniel
Demidik, Maria
Jansen, Karl
Krishnakumar, Raga
Krishnakumar, Rajiv
Laanait, Nouamane
Parida, Laxmi
Saab, Carl
Utro, Filippo
contents Biomarkers play a central role in medicine's gradual progress towards proactive, personalized precision diagnostics and interventions. However, finding biomarkers that provide very early indicators of a change in health status, for example for multi-factorial diseases, has been challenging. Discovery of such biomarkers stands to benefit significantly from advanced information processing and means to detect complex correlations, which quantum computing offers. In this perspective paper, quantum algorithms, particularly in machine learning, are mapped to key applications in biomarker discovery. The opportunities and challenges associated with the algorithms and applications are discussed. The analysis is structured according to different data types - multi-dimensional, time series, and erroneous data - and covers key data modalities in healthcare - electronic health records (EHRs), omics, and medical images. An outlook is provided concerning open research challenges.
format Preprint
id arxiv_https___arxiv_org_abs_2411_10511
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle How quantum computing can enhance biomarker discovery
Flöther, Frederik F.
Blankenberg, Daniel
Demidik, Maria
Jansen, Karl
Krishnakumar, Raga
Krishnakumar, Rajiv
Laanait, Nouamane
Parida, Laxmi
Saab, Carl
Utro, Filippo
Other Quantitative Biology
Quantum Physics
Biomarkers play a central role in medicine's gradual progress towards proactive, personalized precision diagnostics and interventions. However, finding biomarkers that provide very early indicators of a change in health status, for example for multi-factorial diseases, has been challenging. Discovery of such biomarkers stands to benefit significantly from advanced information processing and means to detect complex correlations, which quantum computing offers. In this perspective paper, quantum algorithms, particularly in machine learning, are mapped to key applications in biomarker discovery. The opportunities and challenges associated with the algorithms and applications are discussed. The analysis is structured according to different data types - multi-dimensional, time series, and erroneous data - and covers key data modalities in healthcare - electronic health records (EHRs), omics, and medical images. An outlook is provided concerning open research challenges.
title How quantum computing can enhance biomarker discovery
topic Other Quantitative Biology
Quantum Physics
url https://arxiv.org/abs/2411.10511