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Bibliographic Details
Main Authors: Barash, Danny, Manning, Emilie, Van Vleck, Aidan, Hirsch, Omri, Aye, Kyi Lei, Li, Jingxi, Scumpia, Philip O., Ozcan, Aydogan, Aasi, Sumaira, Rieger, Kerri E., Sarin, Kavita Y., Freifeld, Oren, Winetraub, Yonatan
Format: Preprint
Published: 2024
Subjects:
Online Access:https://arxiv.org/abs/2411.11613
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Table of Contents:
  • Noninvasive optical imaging modalities can probe patient's tissue in 3D and over time generate gigabytes of clinically relevant data per sample. There is a need for AI models to analyze this data and assist clinical workflow. The lack of expert labelers and the large dataset required (>100,000 images) for model training and tuning are the main hurdles in creating foundation models. In this paper we introduce FoundationShift, a method to apply any AI model from computational pathology without retraining. We show our method is more accurate than state of the art models (SAM, MedSAM, SAM-Med2D, CellProfiler, Hover-Net, PLIP, UNI and ChatGPT), with multiple imaging modalities (OCT and RCM). This is achieved without the need for model retraining or fine-tuning. Applying our method to noninvasive in vivo images could enable physicians to readily incorporate optical imaging modalities into their clinical practice, providing real time tissue analysis and improving patient care.