Randomization-based Z-estimation for evaluating average and individual treatment effects

Fuente: arXiv
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Main Authors: Qu, Tianyi, Du, Jiangchuan, Li, Xinran
Format: Preprint
Published: 2024
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author Qu, Tianyi
Du, Jiangchuan
Li, Xinran
author_facet Qu, Tianyi
Du, Jiangchuan
Li, Xinran
contents Randomized experiments have been the gold standard for drawing causal inference. The conventional model-based approach has been one of the most popular ways for analyzing treatment effects from randomized experiments, which is often carried through inference for certain model parameters. In this paper, we provide a systematic investigation of model-based analyses for treatment effects under the randomization-based inference framework. This framework does not impose any distributional assumptions on the outcomes, covariates and their dependence, and utilizes only randomization as the "reasoned basis". We first derive the asymptotic theory for Z-estimation in completely randomized experiments, and propose sandwich-type conservative covariance estimation. We then apply the developed theory to analyze both average and individual treatment effects in randomized experiments. For the average treatment effect, we consider three estimation strategies: model-based, model-imputed, and model-assisted, where the first two can be sensitive to model misspecification or require specific ways for parameter estimation. The model-assisted approach is robust to arbitrary model misspecification and always provides consistent average treatment effect estimation. We propose optimal ways to conduct model-assisted estimation using generally nonlinear least squares for parameter estimation. For the individual treatment effects, we propose to directly model the relationship between individual effects and covariates, and discuss the model's identifiability, inference and interpretation allowing model misspecification.
format Preprint
id arxiv_https___arxiv_org_abs_2411_11737
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Randomization-based Z-estimation for evaluating average and individual treatment effects
Qu, Tianyi
Du, Jiangchuan
Li, Xinran
Methodology
Statistics Theory
Randomized experiments have been the gold standard for drawing causal inference. The conventional model-based approach has been one of the most popular ways for analyzing treatment effects from randomized experiments, which is often carried through inference for certain model parameters. In this paper, we provide a systematic investigation of model-based analyses for treatment effects under the randomization-based inference framework. This framework does not impose any distributional assumptions on the outcomes, covariates and their dependence, and utilizes only randomization as the "reasoned basis". We first derive the asymptotic theory for Z-estimation in completely randomized experiments, and propose sandwich-type conservative covariance estimation. We then apply the developed theory to analyze both average and individual treatment effects in randomized experiments. For the average treatment effect, we consider three estimation strategies: model-based, model-imputed, and model-assisted, where the first two can be sensitive to model misspecification or require specific ways for parameter estimation. The model-assisted approach is robust to arbitrary model misspecification and always provides consistent average treatment effect estimation. We propose optimal ways to conduct model-assisted estimation using generally nonlinear least squares for parameter estimation. For the individual treatment effects, we propose to directly model the relationship between individual effects and covariates, and discuss the model's identifiability, inference and interpretation allowing model misspecification.
title Randomization-based Z-estimation for evaluating average and individual treatment effects
topic Methodology
Statistics Theory
url https://arxiv.org/abs/2411.11737