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Hauptverfasser: Kim, Jiyeong, Chen, Michael L., Rezaei, Shawheen J., Ramirez-Posada, Mariana, Caswell-Jin, Jennifer L., Kurian, Allison W., Riaz, Fauzia, Sarin, Kavita Y., Tang, Jean Y., Asch, Steven M., Linos, Eleni
Format: Preprint
Veröffentlicht: 2024
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Online-Zugang:https://arxiv.org/abs/2411.14456
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author Kim, Jiyeong
Chen, Michael L.
Rezaei, Shawheen J.
Ramirez-Posada, Mariana
Caswell-Jin, Jennifer L.
Kurian, Allison W.
Riaz, Fauzia
Sarin, Kavita Y.
Tang, Jean Y.
Asch, Steven M.
Linos, Eleni
author_facet Kim, Jiyeong
Chen, Michael L.
Rezaei, Shawheen J.
Ramirez-Posada, Mariana
Caswell-Jin, Jennifer L.
Kurian, Allison W.
Riaz, Fauzia
Sarin, Kavita Y.
Tang, Jean Y.
Asch, Steven M.
Linos, Eleni
contents Patient-centered research is increasingly important in narrowing the gap between research and patient care, yet incorporating patient perspectives into health research has been inconsistent. We propose an automated framework leveraging innovative natural language processing (NLP) and artificial intelligence (AI) with patient portal messages to generate research ideas that prioritize important patient issues. We further quantified the quality of AI-generated research topics. To define patient clinical concerns, we analyzed 614,464 patient messages from 25,549 individuals with breast or skin cancer obtained from a large academic hospital (2013 to 2024), constructing a 2-staged unsupervised NLP topic model. Then, we generated research topics to resolve the defined issues using a widely used AI (ChatGPT-4o, OpenAI Inc, April 2024 version) with prompt-engineering strategies. We guided AI to perform multi-level tasks: 1) knowledge interpretation and summarization (e.g., interpreting and summarizing the NLP-defined topics), 2) knowledge generation (e.g., generating research ideas corresponding to patients issues), 3) self-reflection and correction (e.g., ensuring and revising the research ideas after searching for scientific articles), and 4) self-reassurance (e.g., confirming and finalizing the research ideas). Six highly experienced breast oncologists and dermatologists assessed the significance and novelty of AI-generated research topics using a 5-point Likert scale (1-exceptional, 5-poor). One-third of the AI-suggested research topics were highly significant and novel when both scores were lower than the average. Two-thirds of the AI-suggested topics were novel in both cancers. Our findings demonstrate that AI-generated research topics reflecting patient perspectives via a large volume of patient messages can meaningfully guide future directions in patient-centered health research.
format Preprint
id arxiv_https___arxiv_org_abs_2411_14456
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Can Artificial Intelligence Generate Quality Research Topics Reflecting Patient Concerns?
Kim, Jiyeong
Chen, Michael L.
Rezaei, Shawheen J.
Ramirez-Posada, Mariana
Caswell-Jin, Jennifer L.
Kurian, Allison W.
Riaz, Fauzia
Sarin, Kavita Y.
Tang, Jean Y.
Asch, Steven M.
Linos, Eleni
Computation and Language
Artificial Intelligence
Information Retrieval
Patient-centered research is increasingly important in narrowing the gap between research and patient care, yet incorporating patient perspectives into health research has been inconsistent. We propose an automated framework leveraging innovative natural language processing (NLP) and artificial intelligence (AI) with patient portal messages to generate research ideas that prioritize important patient issues. We further quantified the quality of AI-generated research topics. To define patient clinical concerns, we analyzed 614,464 patient messages from 25,549 individuals with breast or skin cancer obtained from a large academic hospital (2013 to 2024), constructing a 2-staged unsupervised NLP topic model. Then, we generated research topics to resolve the defined issues using a widely used AI (ChatGPT-4o, OpenAI Inc, April 2024 version) with prompt-engineering strategies. We guided AI to perform multi-level tasks: 1) knowledge interpretation and summarization (e.g., interpreting and summarizing the NLP-defined topics), 2) knowledge generation (e.g., generating research ideas corresponding to patients issues), 3) self-reflection and correction (e.g., ensuring and revising the research ideas after searching for scientific articles), and 4) self-reassurance (e.g., confirming and finalizing the research ideas). Six highly experienced breast oncologists and dermatologists assessed the significance and novelty of AI-generated research topics using a 5-point Likert scale (1-exceptional, 5-poor). One-third of the AI-suggested research topics were highly significant and novel when both scores were lower than the average. Two-thirds of the AI-suggested topics were novel in both cancers. Our findings demonstrate that AI-generated research topics reflecting patient perspectives via a large volume of patient messages can meaningfully guide future directions in patient-centered health research.
title Can Artificial Intelligence Generate Quality Research Topics Reflecting Patient Concerns?
topic Computation and Language
Artificial Intelligence
Information Retrieval
url https://arxiv.org/abs/2411.14456