Deep operator network models for predicting post-burn contraction

Fuente: arXiv
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Autori principali: Husanovic, Selma, Egberts, Ginger, Heinlein, Alexander, Vermolen, Fred
Natura: Preprint
Pubblicazione: 2024
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author Husanovic, Selma
Egberts, Ginger
Heinlein, Alexander
Vermolen, Fred
author_facet Husanovic, Selma
Egberts, Ginger
Heinlein, Alexander
Vermolen, Fred
contents Burn injuries present a significant global health challenge. Among the most severe long-term consequences are contractures, which can lead to functional impairments and disfigurement. Understanding and predicting the evolution of post-burn wounds is essential for developing effective treatment strategies. Traditional mathematical models, while accurate, are often computationally expensive and time-consuming, limiting their practical application. Recent advancements in machine learning, particularly in deep learning, offer promising alternatives for accelerating these predictions. This study explores the use of a deep operator network (DeepONet), a type of neural operator, as a surrogate model for finite element simulations, aimed at predicting post-burn contraction across multiple wound shapes. A DeepONet was trained on three distinct initial wound shapes, with enhancement made to the architecture by incorporating initial wound shape information and applying sine augmentation to enforce boundary conditions. The performance of the trained DeepONet was evaluated on a test set including finite element simulations based on convex combinations of the three basic wound shapes. The model achieved an $R^2$ score of $0.99$, indicating strong predictive accuracy and generalization. Moreover, the model provided reliable predictions over an extended period of up to one year, with speedups of up to 128-fold on CPU and 235-fold on GPU, compared to the numerical model. These findings suggest that DeepONets can effectively serve as a surrogate for traditional finite element methods in simulating post-burn wound evolution, with potential applications in medical treatment planning.
format Preprint
id arxiv_https___arxiv_org_abs_2411_14555
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Deep operator network models for predicting post-burn contraction
Husanovic, Selma
Egberts, Ginger
Heinlein, Alexander
Vermolen, Fred
Numerical Analysis
Machine Learning
Biological Physics
Tissues and Organs
65M22, 68T07, 65N22, 74L15
Burn injuries present a significant global health challenge. Among the most severe long-term consequences are contractures, which can lead to functional impairments and disfigurement. Understanding and predicting the evolution of post-burn wounds is essential for developing effective treatment strategies. Traditional mathematical models, while accurate, are often computationally expensive and time-consuming, limiting their practical application. Recent advancements in machine learning, particularly in deep learning, offer promising alternatives for accelerating these predictions. This study explores the use of a deep operator network (DeepONet), a type of neural operator, as a surrogate model for finite element simulations, aimed at predicting post-burn contraction across multiple wound shapes. A DeepONet was trained on three distinct initial wound shapes, with enhancement made to the architecture by incorporating initial wound shape information and applying sine augmentation to enforce boundary conditions. The performance of the trained DeepONet was evaluated on a test set including finite element simulations based on convex combinations of the three basic wound shapes. The model achieved an $R^2$ score of $0.99$, indicating strong predictive accuracy and generalization. Moreover, the model provided reliable predictions over an extended period of up to one year, with speedups of up to 128-fold on CPU and 235-fold on GPU, compared to the numerical model. These findings suggest that DeepONets can effectively serve as a surrogate for traditional finite element methods in simulating post-burn wound evolution, with potential applications in medical treatment planning.
title Deep operator network models for predicting post-burn contraction
topic Numerical Analysis
Machine Learning
Biological Physics
Tissues and Organs
65M22, 68T07, 65N22, 74L15
url https://arxiv.org/abs/2411.14555