Generalizable Deep Learning Approach for 3D Particle Imaging using Holographic Microscopy

Fuente: arXiv
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Autori principali: Kumar, Shyam, Hong, Jiarong
Natura: Preprint
Pubblicazione: 2024
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author Kumar, Shyam
Hong, Jiarong
author_facet Kumar, Shyam
Hong, Jiarong
contents Despite its potential for label-free particle diagnostics, holographic microscopy is limited by specialized processing methods that struggle to generalize across diverse settings. We introduce a deep learning architecture leveraging human perception of longitudinal variation of diffracted patterns of particles, which enables highly generalizable analysis of 3D particle information with orders of magnitude improvement in processing speed. Trained with minimal synthetic and real holograms of simple particles, our method demonstrates exceptional performance on various challenging cases including those with high particle concentrations and noises and a wide range of particle sizes, complex shapes, and optical properties exceeding the diversity of the training datasets.
format Preprint
id arxiv_https___arxiv_org_abs_2411_16439
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Generalizable Deep Learning Approach for 3D Particle Imaging using Holographic Microscopy
Kumar, Shyam
Hong, Jiarong
Optics
Despite its potential for label-free particle diagnostics, holographic microscopy is limited by specialized processing methods that struggle to generalize across diverse settings. We introduce a deep learning architecture leveraging human perception of longitudinal variation of diffracted patterns of particles, which enables highly generalizable analysis of 3D particle information with orders of magnitude improvement in processing speed. Trained with minimal synthetic and real holograms of simple particles, our method demonstrates exceptional performance on various challenging cases including those with high particle concentrations and noises and a wide range of particle sizes, complex shapes, and optical properties exceeding the diversity of the training datasets.
title Generalizable Deep Learning Approach for 3D Particle Imaging using Holographic Microscopy
topic Optics
url https://arxiv.org/abs/2411.16439