Rephrasing Electronic Health Records for Pretraining Clinical Language Models

Fuente: arXiv
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Main Authors: Liu, Jinghui, Nguyen, Anthony
Format: Preprint
Published: 2024
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author Liu, Jinghui
Nguyen, Anthony
author_facet Liu, Jinghui
Nguyen, Anthony
contents Clinical language models are important for many applications in healthcare, but their development depends on access to extensive clinical text for pretraining. However, obtaining clinical notes from electronic health records (EHRs) at scale is challenging due to patient privacy concerns. In this study, we rephrase existing clinical notes using LLMs to generate synthetic pretraining corpora, drawing inspiration from previous work on rephrasing web data. We examine four popular small-sized LLMs (<10B) to create synthetic clinical text to pretrain both decoder-based and encoder-based language models. The method yields better results in language modeling and downstream tasks than previous synthesis approaches without referencing real clinical text. We find that augmenting original clinical notes with synthetic corpora from different LLMs improves performances even at a small token budget, showing the potential of this method to support pretraining at the institutional level or be scaled to synthesize large-scale clinical corpora.
format Preprint
id arxiv_https___arxiv_org_abs_2411_18940
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Rephrasing Electronic Health Records for Pretraining Clinical Language Models
Liu, Jinghui
Nguyen, Anthony
Computation and Language
Clinical language models are important for many applications in healthcare, but their development depends on access to extensive clinical text for pretraining. However, obtaining clinical notes from electronic health records (EHRs) at scale is challenging due to patient privacy concerns. In this study, we rephrase existing clinical notes using LLMs to generate synthetic pretraining corpora, drawing inspiration from previous work on rephrasing web data. We examine four popular small-sized LLMs (<10B) to create synthetic clinical text to pretrain both decoder-based and encoder-based language models. The method yields better results in language modeling and downstream tasks than previous synthesis approaches without referencing real clinical text. We find that augmenting original clinical notes with synthetic corpora from different LLMs improves performances even at a small token budget, showing the potential of this method to support pretraining at the institutional level or be scaled to synthesize large-scale clinical corpora.
title Rephrasing Electronic Health Records for Pretraining Clinical Language Models
topic Computation and Language
url https://arxiv.org/abs/2411.18940