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| Main Authors: | , , , |
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| Format: | Preprint |
| Published: |
2024
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| Subjects: | |
| Online Access: | https://arxiv.org/abs/2411.18998 |
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| _version_ | 1866913590082011136 |
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| author | López-Pedrares, Javier Silva, Cristiana J. Vázquez-Cendón, M. Elena Muñuzuri, Alberto P. |
| author_facet | López-Pedrares, Javier Silva, Cristiana J. Vázquez-Cendón, M. Elena Muñuzuri, Alberto P. |
| contents | The emergence of mutant lineages within a viral species has become a public health problem, as the existing treatments and drugs are usually more effective on the original lineages than in the mutant ones. The following manuscript presents mathematical models that describe the emergence of these lineages. In order to reduce the damage and possible casualties that can be attributed to these more contagious microorganisms, the theory of optimal control is introduced and a more sophisticated model is proposed to reduce the mutant growth compared to the original one. The analytical study of these models allows us to obtain an overview of the expected behavior over time, which is validated with numerical simulations. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2411_18998 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | Optimal control applied to viral competition López-Pedrares, Javier Silva, Cristiana J. Vázquez-Cendón, M. Elena Muñuzuri, Alberto P. Mathematical Physics The emergence of mutant lineages within a viral species has become a public health problem, as the existing treatments and drugs are usually more effective on the original lineages than in the mutant ones. The following manuscript presents mathematical models that describe the emergence of these lineages. In order to reduce the damage and possible casualties that can be attributed to these more contagious microorganisms, the theory of optimal control is introduced and a more sophisticated model is proposed to reduce the mutant growth compared to the original one. The analytical study of these models allows us to obtain an overview of the expected behavior over time, which is validated with numerical simulations. |
| title | Optimal control applied to viral competition |
| topic | Mathematical Physics |
| url | https://arxiv.org/abs/2411.18998 |