iSEEtree: interactive explorer for hierarchical data

Fuente: arXiv
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Auteurs principaux: Benedetti, Giulio, Seraidarian, Ely, Pralas, Theotime, Jeba, Akewak, Borman, Tuomas, Lahti, Leo
Format: Preprint
Publié: 2024
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author Benedetti, Giulio
Seraidarian, Ely
Pralas, Theotime
Jeba, Akewak
Borman, Tuomas
Lahti, Leo
author_facet Benedetti, Giulio
Seraidarian, Ely
Pralas, Theotime
Jeba, Akewak
Borman, Tuomas
Lahti, Leo
contents $\textbf{Motivation:}$ Hierarchical data structures are prevalent across several fields of research, as they represent an organised and efficient approach to study complex interconnected systems. Their significance is particularly evident in microbiome analysis, where microbial communities are classified at various taxonomic levels along the phylogenetic tree. In light of this trend, the R/Bioconductor community has established a reproducible analytical framework for hierarchical data, which relies on the highly generic and optimised TreeSummarizedExperiment data container. However, using this framework requires basic proficiency in programming. $\textbf{Results:}$ To reduce the entry requirements, we developed iSEEtree, an R shiny app which provides a visual interface for the analysis and exploration of TreeSummarizedExperiment objects, thereby expanding the interactive graphics capabilities of related work to hierarchical structures. This way, users can interactively explore several aspects of their data without the need for extensive knowledge of R programming. We describe how iSEEtree enables the exploration of hierarchical multi-table data and demonstrate its functionality with applications to microbiome analysis. $\textbf{Availability and Implementation:}$ iSEEtree was implemented in the R programming language and is available on Bioconductor at https://bioconductor.org/packages/iSEEtree under an Artistic 2.0 license. $\textbf{Contact:}$ giulio.benedetti@utu.fi or leo.lahti@utu.fi.
format Preprint
id arxiv_https___arxiv_org_abs_2412_02882
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle iSEEtree: interactive explorer for hierarchical data
Benedetti, Giulio
Seraidarian, Ely
Pralas, Theotime
Jeba, Akewak
Borman, Tuomas
Lahti, Leo
Mathematical Software
Graphics
Genomics
G.4, H.5.2
$\textbf{Motivation:}$ Hierarchical data structures are prevalent across several fields of research, as they represent an organised and efficient approach to study complex interconnected systems. Their significance is particularly evident in microbiome analysis, where microbial communities are classified at various taxonomic levels along the phylogenetic tree. In light of this trend, the R/Bioconductor community has established a reproducible analytical framework for hierarchical data, which relies on the highly generic and optimised TreeSummarizedExperiment data container. However, using this framework requires basic proficiency in programming. $\textbf{Results:}$ To reduce the entry requirements, we developed iSEEtree, an R shiny app which provides a visual interface for the analysis and exploration of TreeSummarizedExperiment objects, thereby expanding the interactive graphics capabilities of related work to hierarchical structures. This way, users can interactively explore several aspects of their data without the need for extensive knowledge of R programming. We describe how iSEEtree enables the exploration of hierarchical multi-table data and demonstrate its functionality with applications to microbiome analysis. $\textbf{Availability and Implementation:}$ iSEEtree was implemented in the R programming language and is available on Bioconductor at https://bioconductor.org/packages/iSEEtree under an Artistic 2.0 license. $\textbf{Contact:}$ giulio.benedetti@utu.fi or leo.lahti@utu.fi.
title iSEEtree: interactive explorer for hierarchical data
topic Mathematical Software
Graphics
Genomics
G.4, H.5.2
url https://arxiv.org/abs/2412.02882