AI-Driven Non-Invasive Detection and Staging of Steatosis in Fatty Liver Disease Using a Novel Cascade Model and Information Fusion Techniques

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Auteurs principaux: Delfan, Niloufar, Moghadam, Pardis Ketabi, Khoshnevisan, Mohammad, Chagahi, Mehdi Hosseini, Hatami, Behzad, Asgharzadeh, Melika, Zali, Mohammadreza, Moshiri, Behzad, Moghaddam, Amin Momeni, Khalafi, Mohammad Amin, Dehnad, Khosrow
Format: Preprint
Publié: 2024
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author Delfan, Niloufar
Moghadam, Pardis Ketabi
Khoshnevisan, Mohammad
Chagahi, Mehdi Hosseini
Hatami, Behzad
Asgharzadeh, Melika
Zali, Mohammadreza
Moshiri, Behzad
Moghaddam, Amin Momeni
Khalafi, Mohammad Amin
Dehnad, Khosrow
author_facet Delfan, Niloufar
Moghadam, Pardis Ketabi
Khoshnevisan, Mohammad
Chagahi, Mehdi Hosseini
Hatami, Behzad
Asgharzadeh, Melika
Zali, Mohammadreza
Moshiri, Behzad
Moghaddam, Amin Momeni
Khalafi, Mohammad Amin
Dehnad, Khosrow
contents Non-alcoholic fatty liver disease (NAFLD) is one of the most widespread liver disorders on a global scale, posing a significant threat of progressing to more severe conditions like nonalcoholic steatohepatitis (NASH), liver fibrosis, cirrhosis, and hepatocellular carcinoma. Diagnosing and staging NAFLD presents challenges due to its non-specific symptoms and the invasive nature of liver biopsies. Our research introduces a novel artificial intelligence cascade model employing ensemble learning and feature fusion techniques. We developed a non-invasive, robust, and reliable diagnostic artificial intelligence tool that utilizes anthropometric and laboratory parameters, facilitating early detection and intervention in NAFLD progression. Our novel artificial intelligence achieved an 86% accuracy rate for the NASH steatosis staging task (non-NASH, steatosis grade 1, steatosis grade 2, and steatosis grade 3) and an impressive 96% AUC-ROC for distinguishing between NASH (steatosis grade 1, grade 2, and grade3) and non-NASH cases, outperforming current state-of-the-art models. This notable improvement in diagnostic performance underscores the potential application of artificial intelligence in the early diagnosis and treatment of NAFLD, leading to better patient outcomes and a reduced healthcare burden associated with advanced liver disease.
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id arxiv_https___arxiv_org_abs_2412_04884
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publishDate 2024
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spellingShingle AI-Driven Non-Invasive Detection and Staging of Steatosis in Fatty Liver Disease Using a Novel Cascade Model and Information Fusion Techniques
Delfan, Niloufar
Moghadam, Pardis Ketabi
Khoshnevisan, Mohammad
Chagahi, Mehdi Hosseini
Hatami, Behzad
Asgharzadeh, Melika
Zali, Mohammadreza
Moshiri, Behzad
Moghaddam, Amin Momeni
Khalafi, Mohammad Amin
Dehnad, Khosrow
Machine Learning
Artificial Intelligence
Computer Vision and Pattern Recognition
Non-alcoholic fatty liver disease (NAFLD) is one of the most widespread liver disorders on a global scale, posing a significant threat of progressing to more severe conditions like nonalcoholic steatohepatitis (NASH), liver fibrosis, cirrhosis, and hepatocellular carcinoma. Diagnosing and staging NAFLD presents challenges due to its non-specific symptoms and the invasive nature of liver biopsies. Our research introduces a novel artificial intelligence cascade model employing ensemble learning and feature fusion techniques. We developed a non-invasive, robust, and reliable diagnostic artificial intelligence tool that utilizes anthropometric and laboratory parameters, facilitating early detection and intervention in NAFLD progression. Our novel artificial intelligence achieved an 86% accuracy rate for the NASH steatosis staging task (non-NASH, steatosis grade 1, steatosis grade 2, and steatosis grade 3) and an impressive 96% AUC-ROC for distinguishing between NASH (steatosis grade 1, grade 2, and grade3) and non-NASH cases, outperforming current state-of-the-art models. This notable improvement in diagnostic performance underscores the potential application of artificial intelligence in the early diagnosis and treatment of NAFLD, leading to better patient outcomes and a reduced healthcare burden associated with advanced liver disease.
title AI-Driven Non-Invasive Detection and Staging of Steatosis in Fatty Liver Disease Using a Novel Cascade Model and Information Fusion Techniques
topic Machine Learning
Artificial Intelligence
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2412.04884