Parkinson's Disease Diagnosis Through Deep Learning: A Novel LSTM-Based Approach for Freezing of Gait Detection

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Hauptverfasser: Mir, Aqib Nazir, Nissar, Iqra, Ahmed, Mumtaz, Masood, Sarfaraz, Rizvi, Danish Raza
Format: Preprint
Veröffentlicht: 2024
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author Mir, Aqib Nazir
Nissar, Iqra
Ahmed, Mumtaz
Masood, Sarfaraz
Rizvi, Danish Raza
author_facet Mir, Aqib Nazir
Nissar, Iqra
Ahmed, Mumtaz
Masood, Sarfaraz
Rizvi, Danish Raza
contents Deep learning holds tremendous potential in healthcare for uncovering hidden patterns within extensive clinical datasets, aiding in the diagnosis of various diseases. Parkinson's disease (PD) is a neurodegenerative condition characterized by the deterioration of brain function. In the initial stages of PD, automatic diagnosis poses a challenge due to the similarity in behavior between individuals with PD and those who are healthy. Our objective is to propose an effective model that can aid in the early detection of Parkinson's disease. We employed the VGRF gait signal dataset sourced from Physionet for distinguishing between healthy individuals and those diagnosed with Parkinson's disease. This paper introduces a novel deep learning architecture based on the LSTM network for automatically detecting freezing of gait episodes in Parkinson's disease patients. In contrast to conventional machine learning algorithms, this method eliminates manual feature engineering and proficiently captures prolonged temporal dependencies in gait patterns, thereby improving the diagnosis of Parkinson's disease. The LSTM network resolves the issue of vanishing gradients by employing memory blocks in place of self-connected hidden units, allowing for optimal information assimilation. To prevent overfitting, dropout and L2 regularization techniques have been employed. Additionally, the stochastic gradient-based optimizer Adam is used for the optimization process. The results indicate that our proposed approach surpasses current state-of-the-art models in FOG episode detection, achieving an accuracy of 97.71%, sensitivity of 99%, precision of 98%, and specificity of 96%. This demonstrates its potential as a superior classification method for Parkinson's disease detection.
format Preprint
id arxiv_https___arxiv_org_abs_2412_06709
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Parkinson's Disease Diagnosis Through Deep Learning: A Novel LSTM-Based Approach for Freezing of Gait Detection
Mir, Aqib Nazir
Nissar, Iqra
Ahmed, Mumtaz
Masood, Sarfaraz
Rizvi, Danish Raza
Computer Vision and Pattern Recognition
Artificial Intelligence
Deep learning holds tremendous potential in healthcare for uncovering hidden patterns within extensive clinical datasets, aiding in the diagnosis of various diseases. Parkinson's disease (PD) is a neurodegenerative condition characterized by the deterioration of brain function. In the initial stages of PD, automatic diagnosis poses a challenge due to the similarity in behavior between individuals with PD and those who are healthy. Our objective is to propose an effective model that can aid in the early detection of Parkinson's disease. We employed the VGRF gait signal dataset sourced from Physionet for distinguishing between healthy individuals and those diagnosed with Parkinson's disease. This paper introduces a novel deep learning architecture based on the LSTM network for automatically detecting freezing of gait episodes in Parkinson's disease patients. In contrast to conventional machine learning algorithms, this method eliminates manual feature engineering and proficiently captures prolonged temporal dependencies in gait patterns, thereby improving the diagnosis of Parkinson's disease. The LSTM network resolves the issue of vanishing gradients by employing memory blocks in place of self-connected hidden units, allowing for optimal information assimilation. To prevent overfitting, dropout and L2 regularization techniques have been employed. Additionally, the stochastic gradient-based optimizer Adam is used for the optimization process. The results indicate that our proposed approach surpasses current state-of-the-art models in FOG episode detection, achieving an accuracy of 97.71%, sensitivity of 99%, precision of 98%, and specificity of 96%. This demonstrates its potential as a superior classification method for Parkinson's disease detection.
title Parkinson's Disease Diagnosis Through Deep Learning: A Novel LSTM-Based Approach for Freezing of Gait Detection
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2412.06709