A model for the dynamics of COVID-19 infection transmission in human with latent delay

Fuente: arXiv
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Main Authors: Chatterjee, Amar N., Abraha, Teklebirhan, Basir, Fahad Al, Torres, Delfim F. M.
Format: Preprint
Published: 2024
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_version_ 1866910780565225472
author Chatterjee, Amar N.
Abraha, Teklebirhan
Basir, Fahad Al
Torres, Delfim F. M.
author_facet Chatterjee, Amar N.
Abraha, Teklebirhan
Basir, Fahad Al
Torres, Delfim F. M.
contents In this research, we have derived a mathematical model for within human dynamics of COVID-19 infection using delay differential equations. The new model considers a 'latent period' and 'the time for immune response' as delay parameters, allowing us to study the effects of time delays in human COVID-19 infection. We have determined the equilibrium points and analyzed their stability. The disease-free equilibrium is stable when the basic reproduction number, $R_0$, is below unity. Stability switch of the endemic equilibrium occurs through Hopf-bifurcation. This study shows that the effect of latent delay is stabilizing whereas immune response delay has a destabilizing nature.
format Preprint
id arxiv_https___arxiv_org_abs_2412_12315
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle A model for the dynamics of COVID-19 infection transmission in human with latent delay
Chatterjee, Amar N.
Abraha, Teklebirhan
Basir, Fahad Al
Torres, Delfim F. M.
Populations and Evolution
Dynamical Systems
Cell Behavior
34H20, 34K20, 92-10
In this research, we have derived a mathematical model for within human dynamics of COVID-19 infection using delay differential equations. The new model considers a 'latent period' and 'the time for immune response' as delay parameters, allowing us to study the effects of time delays in human COVID-19 infection. We have determined the equilibrium points and analyzed their stability. The disease-free equilibrium is stable when the basic reproduction number, $R_0$, is below unity. Stability switch of the endemic equilibrium occurs through Hopf-bifurcation. This study shows that the effect of latent delay is stabilizing whereas immune response delay has a destabilizing nature.
title A model for the dynamics of COVID-19 infection transmission in human with latent delay
topic Populations and Evolution
Dynamical Systems
Cell Behavior
34H20, 34K20, 92-10
url https://arxiv.org/abs/2412.12315