Starting a Synthetic Biological Intelligence Lab from Scratch

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Main Authors: Tanveer, Md Sayed, Patel, Dhruvik, Schweiger, Hunter E., Abu-Bonsrah, Kwaku Dad, Watmuff, Brad, Azadi, Azin, Pryshchep, Sergey, Narayanan, Karthikeyan, Puleo, Christopher, Natarajan, Kannathal, Mostajo-Radji, Mohammed A., Kagan, Brett J., Wang, Ge
Format: Preprint
Published: 2024
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author Tanveer, Md Sayed
Patel, Dhruvik
Schweiger, Hunter E.
Abu-Bonsrah, Kwaku Dad
Watmuff, Brad
Azadi, Azin
Pryshchep, Sergey
Narayanan, Karthikeyan
Puleo, Christopher
Natarajan, Kannathal
Mostajo-Radji, Mohammed A.
Kagan, Brett J.
Wang, Ge
author_facet Tanveer, Md Sayed
Patel, Dhruvik
Schweiger, Hunter E.
Abu-Bonsrah, Kwaku Dad
Watmuff, Brad
Azadi, Azin
Pryshchep, Sergey
Narayanan, Karthikeyan
Puleo, Christopher
Natarajan, Kannathal
Mostajo-Radji, Mohammed A.
Kagan, Brett J.
Wang, Ge
contents With the recent advancements in artificial intelligence, researchers and industries are deploying gigantic models trained on billions of samples. While training these models consumes a huge amount of energy, human brains produce similar outputs (along with other capabilities) with massively lower data and energy requirements. For this reason, more researchers are increasingly considering alternatives. One of these alternatives is known as synthetic biological intelligence, which involves training \textit{in vitro} neurons for goal-directed tasks. This multidisciplinary field requires knowledge of tissue engineering, bio-materials, digital signal processing, computer programming, neuroscience, and even artificial intelligence. The multidisciplinary requirements make starting synthetic biological intelligence research highly non-trivial and time-consuming. Generally, most labs either specialize in the biological aspects or the computational ones. Here, we propose how a lab focusing on computational aspects, including machine learning and device interfacing, can start working on synthetic biological intelligence, including organoid intelligence. We will also discuss computational aspects, which can be helpful for labs that focus on biological research. To facilitate synthetic biological intelligence research, we will describe such a general process step by step, including risks and precautions that could lead to substantial delay or additional cost.
format Preprint
id arxiv_https___arxiv_org_abs_2412_14112
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Starting a Synthetic Biological Intelligence Lab from Scratch
Tanveer, Md Sayed
Patel, Dhruvik
Schweiger, Hunter E.
Abu-Bonsrah, Kwaku Dad
Watmuff, Brad
Azadi, Azin
Pryshchep, Sergey
Narayanan, Karthikeyan
Puleo, Christopher
Natarajan, Kannathal
Mostajo-Radji, Mohammed A.
Kagan, Brett J.
Wang, Ge
Neurons and Cognition
With the recent advancements in artificial intelligence, researchers and industries are deploying gigantic models trained on billions of samples. While training these models consumes a huge amount of energy, human brains produce similar outputs (along with other capabilities) with massively lower data and energy requirements. For this reason, more researchers are increasingly considering alternatives. One of these alternatives is known as synthetic biological intelligence, which involves training \textit{in vitro} neurons for goal-directed tasks. This multidisciplinary field requires knowledge of tissue engineering, bio-materials, digital signal processing, computer programming, neuroscience, and even artificial intelligence. The multidisciplinary requirements make starting synthetic biological intelligence research highly non-trivial and time-consuming. Generally, most labs either specialize in the biological aspects or the computational ones. Here, we propose how a lab focusing on computational aspects, including machine learning and device interfacing, can start working on synthetic biological intelligence, including organoid intelligence. We will also discuss computational aspects, which can be helpful for labs that focus on biological research. To facilitate synthetic biological intelligence research, we will describe such a general process step by step, including risks and precautions that could lead to substantial delay or additional cost.
title Starting a Synthetic Biological Intelligence Lab from Scratch
topic Neurons and Cognition
url https://arxiv.org/abs/2412.14112