Classifier-guided registration of coronary CT angiography and intravascular ultrasound

Fuente: arXiv
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Main Authors: van Herten, R. L. M., Henriques, José P., Planken, R. Nils, Daemen, Joost, Hartman, Eline M. J., Wentzel, Jolanda J., Išgum, Ivana
Format: Preprint
Published: 2024
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author van Herten, R. L. M.
Henriques, José P.
Planken, R. Nils
Daemen, Joost
Hartman, Eline M. J.
Wentzel, Jolanda J.
Išgum, Ivana
author_facet van Herten, R. L. M.
Henriques, José P.
Planken, R. Nils
Daemen, Joost
Hartman, Eline M. J.
Wentzel, Jolanda J.
Išgum, Ivana
contents Coronary CT angiography (CCTA) and intravascular ultrasound (IVUS) provide complementary information for coronary artery disease assessment, making their registration valuable for comprehensive analysis. However, existing registration methods require manual interaction or extensive segmentations, limiting their practical application. In this work, we present a fully automatic framework for CCTA-IVUS registration using deep learning-based feature detection and a differentiable image registration module. Our approach leverages a convolutional neural network trained to identify key anatomical features from polar-transformed multiplanar reformatted CCTA or IVUS data. These detected anatomical featuers subsequently guide a differentiable registration module to optimize transformation parameters of an automatically extracted coronary artery centerline. The method does not require landmark selection or segmentations as input, while accounting for the presence of IVUS guidewire artifacts. Evaluated on 48 clinical cases with reference CCTA centerlines corresponding to IVUS pullback, our method achieved successful registration in 83.3\% of cases, with a median centerline overlap F$_1$-score of 0.982 and median cosine similarities of 0.940 and 0.944 for cross-sectional plane orientation. Our results demonstrate that automatically detected anatomical features can be leveraged for accurate registration. The fully automatic nature of the approach represents a significant step toward streamlined multimodal coronary analysis, potentially facilitating large-scale studies of coronary plaque characteristics across modalities.
format Preprint
id arxiv_https___arxiv_org_abs_2412_17100
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Classifier-guided registration of coronary CT angiography and intravascular ultrasound
van Herten, R. L. M.
Henriques, José P.
Planken, R. Nils
Daemen, Joost
Hartman, Eline M. J.
Wentzel, Jolanda J.
Išgum, Ivana
Image and Video Processing
Coronary CT angiography (CCTA) and intravascular ultrasound (IVUS) provide complementary information for coronary artery disease assessment, making their registration valuable for comprehensive analysis. However, existing registration methods require manual interaction or extensive segmentations, limiting their practical application. In this work, we present a fully automatic framework for CCTA-IVUS registration using deep learning-based feature detection and a differentiable image registration module. Our approach leverages a convolutional neural network trained to identify key anatomical features from polar-transformed multiplanar reformatted CCTA or IVUS data. These detected anatomical featuers subsequently guide a differentiable registration module to optimize transformation parameters of an automatically extracted coronary artery centerline. The method does not require landmark selection or segmentations as input, while accounting for the presence of IVUS guidewire artifacts. Evaluated on 48 clinical cases with reference CCTA centerlines corresponding to IVUS pullback, our method achieved successful registration in 83.3\% of cases, with a median centerline overlap F$_1$-score of 0.982 and median cosine similarities of 0.940 and 0.944 for cross-sectional plane orientation. Our results demonstrate that automatically detected anatomical features can be leveraged for accurate registration. The fully automatic nature of the approach represents a significant step toward streamlined multimodal coronary analysis, potentially facilitating large-scale studies of coronary plaque characteristics across modalities.
title Classifier-guided registration of coronary CT angiography and intravascular ultrasound
topic Image and Video Processing
url https://arxiv.org/abs/2412.17100