7 Tesla multimodal MRI dataset of ex-vivo human brain

Fuente: arXiv
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Autores principales: Zhu, Qinfeng, Li, Sihui, Cao, Zuozhen, Shen, Yao, Xu, Haoan, Xu, Guojun, Li, Haotian, Zhu, Keqing, Zhao, Zhiyong, Zhang, Jing, Wu, Dan
Formato: Preprint
Publicado: 2024
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author Zhu, Qinfeng
Li, Sihui
Cao, Zuozhen
Shen, Yao
Xu, Haoan
Xu, Guojun
Li, Haotian
Zhu, Keqing
Zhao, Zhiyong
Zhang, Jing
Wu, Dan
author_facet Zhu, Qinfeng
Li, Sihui
Cao, Zuozhen
Shen, Yao
Xu, Haoan
Xu, Guojun
Li, Haotian
Zhu, Keqing
Zhao, Zhiyong
Zhang, Jing
Wu, Dan
contents Ex-vivo MRI offers invaluable insights into the complexity of the human brain, enabling high-resolution anatomical delineation and integration with histopathology, and thus, contributes to both basic and clinical studies on normal and pathological brains. However, ex-vivo MRI is challenging in sample preparation, acquisition, and data analysis, and existing ex-vivo MRI datasets are often single image modality and lack of ethnic diversity. In our study, we aimed to address these limitations by constructing a comprehensive multimodal MRI database acquired from six ex-vivo Chinese human brains. This database included structural MRI, high-angular resolution diffusion MRI, quantitative susceptibility mapping, and quantitative T1 and T2 maps, which enabled multifaceted depiction of brain microstructure and connectivity. Furthermore, we generated population-averaged multimodal templates and the segmentation labels to facilitate analysis of ex-vivo brain MRI. This public database offers a collection of high-resolution and multi-parametric ex-vivo human brain MRI and filled the gap of lacking Asian brain samples in existing databases.
format Preprint
id arxiv_https___arxiv_org_abs_2412_17816
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle 7 Tesla multimodal MRI dataset of ex-vivo human brain
Zhu, Qinfeng
Li, Sihui
Cao, Zuozhen
Shen, Yao
Xu, Haoan
Xu, Guojun
Li, Haotian
Zhu, Keqing
Zhao, Zhiyong
Zhang, Jing
Wu, Dan
Quantitative Methods
Ex-vivo MRI offers invaluable insights into the complexity of the human brain, enabling high-resolution anatomical delineation and integration with histopathology, and thus, contributes to both basic and clinical studies on normal and pathological brains. However, ex-vivo MRI is challenging in sample preparation, acquisition, and data analysis, and existing ex-vivo MRI datasets are often single image modality and lack of ethnic diversity. In our study, we aimed to address these limitations by constructing a comprehensive multimodal MRI database acquired from six ex-vivo Chinese human brains. This database included structural MRI, high-angular resolution diffusion MRI, quantitative susceptibility mapping, and quantitative T1 and T2 maps, which enabled multifaceted depiction of brain microstructure and connectivity. Furthermore, we generated population-averaged multimodal templates and the segmentation labels to facilitate analysis of ex-vivo brain MRI. This public database offers a collection of high-resolution and multi-parametric ex-vivo human brain MRI and filled the gap of lacking Asian brain samples in existing databases.
title 7 Tesla multimodal MRI dataset of ex-vivo human brain
topic Quantitative Methods
url https://arxiv.org/abs/2412.17816