Research on the Proximity Relationships of Psychosomatic Disease Knowledge Graph Modules Extracted by Large Language Models

Fuente: arXiv
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Autori principali: Zhou, Zihan, Zeng, Ziyi, Jiang, Wenhao, Zhu, Yihui, Mao, Jiaxin, Yuan, Yonggui, Xia, Min, Zhao, Shubin, Yao, Mengyu, Chen, Yunqian
Natura: Preprint
Pubblicazione: 2024
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author Zhou, Zihan
Zeng, Ziyi
Jiang, Wenhao
Zhu, Yihui
Mao, Jiaxin
Yuan, Yonggui
Xia, Min
Zhao, Shubin
Yao, Mengyu
Chen, Yunqian
author_facet Zhou, Zihan
Zeng, Ziyi
Jiang, Wenhao
Zhu, Yihui
Mao, Jiaxin
Yuan, Yonggui
Xia, Min
Zhao, Shubin
Yao, Mengyu
Chen, Yunqian
contents As social changes accelerate, the incidence of psychosomatic disorders has significantly increased, becoming a major challenge in global health issues. This necessitates an innovative knowledge system and analytical methods to aid in diagnosis and treatment. Here, we establish the ontology model and entity types, using the BERT model and LoRA-tuned LLM for named entity recognition, constructing the knowledge graph with 9668 triples. Next, by analyzing the network distances between disease, symptom, and drug modules, it was found that closer network distances among diseases can predict greater similarities in their clinical manifestations, treatment approaches, and psychological mechanisms, and closer distances between symptoms indicate that they are more likely to co-occur. Lastly, by comparing the proximity d and proximity z score, it was shown that symptom-disease pairs in primary diagnostic relationships have a stronger association and are of higher referential value than those in diagnostic relationships. The research results revealed the potential connections between diseases, co-occurring symptoms, and similarities in treatment strategies, providing new perspectives for the diagnosis and treatment of psychosomatic disorders and valuable information for future mental health research and practice.
format Preprint
id arxiv_https___arxiv_org_abs_2412_18419
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Research on the Proximity Relationships of Psychosomatic Disease Knowledge Graph Modules Extracted by Large Language Models
Zhou, Zihan
Zeng, Ziyi
Jiang, Wenhao
Zhu, Yihui
Mao, Jiaxin
Yuan, Yonggui
Xia, Min
Zhao, Shubin
Yao, Mengyu
Chen, Yunqian
Artificial Intelligence
As social changes accelerate, the incidence of psychosomatic disorders has significantly increased, becoming a major challenge in global health issues. This necessitates an innovative knowledge system and analytical methods to aid in diagnosis and treatment. Here, we establish the ontology model and entity types, using the BERT model and LoRA-tuned LLM for named entity recognition, constructing the knowledge graph with 9668 triples. Next, by analyzing the network distances between disease, symptom, and drug modules, it was found that closer network distances among diseases can predict greater similarities in their clinical manifestations, treatment approaches, and psychological mechanisms, and closer distances between symptoms indicate that they are more likely to co-occur. Lastly, by comparing the proximity d and proximity z score, it was shown that symptom-disease pairs in primary diagnostic relationships have a stronger association and are of higher referential value than those in diagnostic relationships. The research results revealed the potential connections between diseases, co-occurring symptoms, and similarities in treatment strategies, providing new perspectives for the diagnosis and treatment of psychosomatic disorders and valuable information for future mental health research and practice.
title Research on the Proximity Relationships of Psychosomatic Disease Knowledge Graph Modules Extracted by Large Language Models
topic Artificial Intelligence
url https://arxiv.org/abs/2412.18419