Nonlinear Response Identities and Bounds for Nonequilibrium Steady States

Fuente: arXiv
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Autori principali: Bao, Ruicheng, Liang, Shiling
Natura: Preprint
Pubblicazione: 2024
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author Bao, Ruicheng
Liang, Shiling
author_facet Bao, Ruicheng
Liang, Shiling
contents Understanding how systems respond to external perturbations is fundamental to statistical physics. For systems far from equilibrium, a general framework for response remains elusive. While progress has been made on the linear response of nonequilibrium systems, a theory for the nonlinear regime under finite perturbations has been lacking. Here, building on a novel connection between response and mean first-passage times in continuous-time Markov chains, we derive a comprehensive theory for the nonlinear response to archetypal local perturbations. We establish an exact identity that universally connects the nonlinear response of any observable to its linear counterpart via a simple scaling factor. This identity directly yields universal bounds on the response magnitude. Furthermore, we establish a universal bound on response resolution -- an inequality constraining an observable's change by its intrinsic fluctuations -- thereby setting a fundamental limit on signal-to-noise ratio. These results provide a rigorous and general framework for analyzing nonlinear response far from equilibrium, which we illustrate with an application to transcriptional regulation.
format Preprint
id arxiv_https___arxiv_org_abs_2412_19602
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Nonlinear Response Identities and Bounds for Nonequilibrium Steady States
Bao, Ruicheng
Liang, Shiling
Statistical Mechanics
Biological Physics
Understanding how systems respond to external perturbations is fundamental to statistical physics. For systems far from equilibrium, a general framework for response remains elusive. While progress has been made on the linear response of nonequilibrium systems, a theory for the nonlinear regime under finite perturbations has been lacking. Here, building on a novel connection between response and mean first-passage times in continuous-time Markov chains, we derive a comprehensive theory for the nonlinear response to archetypal local perturbations. We establish an exact identity that universally connects the nonlinear response of any observable to its linear counterpart via a simple scaling factor. This identity directly yields universal bounds on the response magnitude. Furthermore, we establish a universal bound on response resolution -- an inequality constraining an observable's change by its intrinsic fluctuations -- thereby setting a fundamental limit on signal-to-noise ratio. These results provide a rigorous and general framework for analyzing nonlinear response far from equilibrium, which we illustrate with an application to transcriptional regulation.
title Nonlinear Response Identities and Bounds for Nonequilibrium Steady States
topic Statistical Mechanics
Biological Physics
url https://arxiv.org/abs/2412.19602