Enhancing Contrastive Learning for Retinal Imaging via Adjusted Augmentation Scales

Fuente: arXiv
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Autores principales: Cheng, Zijie, Li, Boxuan, Altmann, André, Keane, Pearse A, Zhou, Yukun
Formato: Preprint
Publicado: 2025
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author Cheng, Zijie
Li, Boxuan
Altmann, André
Keane, Pearse A
Zhou, Yukun
author_facet Cheng, Zijie
Li, Boxuan
Altmann, André
Keane, Pearse A
Zhou, Yukun
contents Contrastive learning, a prominent approach within self-supervised learning, has demonstrated significant effectiveness in developing generalizable models for various applications involving natural images. However, recent research indicates that these successes do not necessarily extend to the medical imaging domain. In this paper, we investigate the reasons for this suboptimal performance and hypothesize that the dense distribution of medical images poses challenges to the pretext tasks in contrastive learning, particularly in constructing positive and negative pairs. We explore model performance under different augmentation strategies and compare the results to those achieved with strong augmentations. Our study includes six publicly available datasets covering multiple clinically relevant tasks. We further assess the model's generalizability through external evaluations. The model pre-trained with weak augmentation outperforms those with strong augmentation, improving AUROC from 0.838 to 0.848 and AUPR from 0.523 to 0.597 on MESSIDOR2, and showing similar enhancements across other datasets. Our findings suggest that optimizing the scale of augmentation is critical for enhancing the efficacy of contrastive learning in medical imaging.
format Preprint
id arxiv_https___arxiv_org_abs_2501_02451
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Enhancing Contrastive Learning for Retinal Imaging via Adjusted Augmentation Scales
Cheng, Zijie
Li, Boxuan
Altmann, André
Keane, Pearse A
Zhou, Yukun
Computer Vision and Pattern Recognition
Artificial Intelligence
Contrastive learning, a prominent approach within self-supervised learning, has demonstrated significant effectiveness in developing generalizable models for various applications involving natural images. However, recent research indicates that these successes do not necessarily extend to the medical imaging domain. In this paper, we investigate the reasons for this suboptimal performance and hypothesize that the dense distribution of medical images poses challenges to the pretext tasks in contrastive learning, particularly in constructing positive and negative pairs. We explore model performance under different augmentation strategies and compare the results to those achieved with strong augmentations. Our study includes six publicly available datasets covering multiple clinically relevant tasks. We further assess the model's generalizability through external evaluations. The model pre-trained with weak augmentation outperforms those with strong augmentation, improving AUROC from 0.838 to 0.848 and AUPR from 0.523 to 0.597 on MESSIDOR2, and showing similar enhancements across other datasets. Our findings suggest that optimizing the scale of augmentation is critical for enhancing the efficacy of contrastive learning in medical imaging.
title Enhancing Contrastive Learning for Retinal Imaging via Adjusted Augmentation Scales
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2501.02451