Bridged Semantic Alignment for Zero-shot 3D Medical Image Diagnosis

Fuente: arXiv
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Autores principales: Lai, Haoran, Jiang, Zihang, Yao, Qingsong, Wang, Rongsheng, He, Zhiyang, Tao, Xiaodong, Lv, Weifu, Wei, Wei, Zhou, S. Kevin
Formato: Preprint
Publicado: 2025
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author Lai, Haoran
Jiang, Zihang
Yao, Qingsong
Wang, Rongsheng
He, Zhiyang
Tao, Xiaodong
Lv, Weifu
Wei, Wei
Zhou, S. Kevin
author_facet Lai, Haoran
Jiang, Zihang
Yao, Qingsong
Wang, Rongsheng
He, Zhiyang
Tao, Xiaodong
Lv, Weifu
Wei, Wei
Zhou, S. Kevin
contents 3D medical images such as computed tomography are widely used in clinical practice, offering a great potential for automatic diagnosis. Supervised learning-based approaches have achieved significant progress but rely heavily on extensive manual annotations, limited by the availability of training data and the diversity of abnormality types. Vision-language alignment (VLA) offers a promising alternative by enabling zero-shot learning without additional annotations. However, we empirically discover that the visual and textural embeddings after alignment endeavors from existing VLA methods form two well-separated clusters, presenting a wide gap to be bridged. To bridge this gap, we propose a Bridged Semantic Alignment (BrgSA) framework. First, we utilize a large language model to perform semantic summarization of reports, extracting high-level semantic information. Second, we design a Cross-Modal Knowledge Interaction module that leverages a cross-modal knowledge bank as a semantic bridge, facilitating interaction between the two modalities, narrowing the gap, and improving their alignment. To comprehensively evaluate our method, we construct a benchmark dataset that includes 15 underrepresented abnormalities as well as utilize two existing benchmark datasets. Experimental results demonstrate that BrgSA achieves state-of-the-art performances on both public benchmark datasets and our custom-labeled dataset, with significant improvements in zero-shot diagnosis of underrepresented abnormalities.
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institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Bridged Semantic Alignment for Zero-shot 3D Medical Image Diagnosis
Lai, Haoran
Jiang, Zihang
Yao, Qingsong
Wang, Rongsheng
He, Zhiyang
Tao, Xiaodong
Lv, Weifu
Wei, Wei
Zhou, S. Kevin
Computer Vision and Pattern Recognition
3D medical images such as computed tomography are widely used in clinical practice, offering a great potential for automatic diagnosis. Supervised learning-based approaches have achieved significant progress but rely heavily on extensive manual annotations, limited by the availability of training data and the diversity of abnormality types. Vision-language alignment (VLA) offers a promising alternative by enabling zero-shot learning without additional annotations. However, we empirically discover that the visual and textural embeddings after alignment endeavors from existing VLA methods form two well-separated clusters, presenting a wide gap to be bridged. To bridge this gap, we propose a Bridged Semantic Alignment (BrgSA) framework. First, we utilize a large language model to perform semantic summarization of reports, extracting high-level semantic information. Second, we design a Cross-Modal Knowledge Interaction module that leverages a cross-modal knowledge bank as a semantic bridge, facilitating interaction between the two modalities, narrowing the gap, and improving their alignment. To comprehensively evaluate our method, we construct a benchmark dataset that includes 15 underrepresented abnormalities as well as utilize two existing benchmark datasets. Experimental results demonstrate that BrgSA achieves state-of-the-art performances on both public benchmark datasets and our custom-labeled dataset, with significant improvements in zero-shot diagnosis of underrepresented abnormalities.
title Bridged Semantic Alignment for Zero-shot 3D Medical Image Diagnosis
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2501.03565