LLAMADRS: Evaluating Open-Source LLMs on Real Clinical Interviews--To Reason or Not to Reason?

Fuente: arXiv
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Main Authors: Kebe, Gaoussou Youssouf, Girard, Jeffrey M., Liebenthal, Einat, Baker, Justin, De la Torre, Fernando, Morency, Louis-Philippe
Format: Preprint
Published: 2025
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author Kebe, Gaoussou Youssouf
Girard, Jeffrey M.
Liebenthal, Einat
Baker, Justin
De la Torre, Fernando
Morency, Louis-Philippe
author_facet Kebe, Gaoussou Youssouf
Girard, Jeffrey M.
Liebenthal, Einat
Baker, Justin
De la Torre, Fernando
Morency, Louis-Philippe
contents Large language models (LLMs) excel on many NLP benchmarks, but their behavior on real-world, semi-structured prediction remains underexplored. We present LlaMADRS, a benchmark for structured clinical assessment from dialogue built on the CAMI corpus of psychiatric interviews, comprising 5,804 expert annotations across 541 sessions. We evaluate 25 open-source models (standard and reasoning-augmented; 0.6B--400B parameters) and generate over 400,000 predictions. Our results demonstrate that strong open-source LLMs achieve item-level accuracy with residual error below clinically substantial thresholds. Additionally, an Item-then-Sum (ItS) strategy, assessing symptoms individually through discrete LLM calls before synthesizing final scores, significantly reduces error relative to Direct Total Score (DTS) prediction across most model architectures and scales, despite reasoning models attempting similar decomposition in the reasoning traces of their DTS predictions. In fact, we find that performance gains attributed to "reasoning" depend fundamentally on prompt design: standard models equipped with structured task definitions and examples match reasoning-augmented counterparts. Among the latter, longer reasoning traces correlate with reduced error; while higher model scale does across both architectures. Our results clarify when and why reasoning helps and offer actionable guidance for deploying LLMs in semi-structured clinical assessment.
format Preprint
id arxiv_https___arxiv_org_abs_2501_03624
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle LLAMADRS: Evaluating Open-Source LLMs on Real Clinical Interviews--To Reason or Not to Reason?
Kebe, Gaoussou Youssouf
Girard, Jeffrey M.
Liebenthal, Einat
Baker, Justin
De la Torre, Fernando
Morency, Louis-Philippe
Human-Computer Interaction
Computation and Language
I.2.7
Large language models (LLMs) excel on many NLP benchmarks, but their behavior on real-world, semi-structured prediction remains underexplored. We present LlaMADRS, a benchmark for structured clinical assessment from dialogue built on the CAMI corpus of psychiatric interviews, comprising 5,804 expert annotations across 541 sessions. We evaluate 25 open-source models (standard and reasoning-augmented; 0.6B--400B parameters) and generate over 400,000 predictions. Our results demonstrate that strong open-source LLMs achieve item-level accuracy with residual error below clinically substantial thresholds. Additionally, an Item-then-Sum (ItS) strategy, assessing symptoms individually through discrete LLM calls before synthesizing final scores, significantly reduces error relative to Direct Total Score (DTS) prediction across most model architectures and scales, despite reasoning models attempting similar decomposition in the reasoning traces of their DTS predictions. In fact, we find that performance gains attributed to "reasoning" depend fundamentally on prompt design: standard models equipped with structured task definitions and examples match reasoning-augmented counterparts. Among the latter, longer reasoning traces correlate with reduced error; while higher model scale does across both architectures. Our results clarify when and why reasoning helps and offer actionable guidance for deploying LLMs in semi-structured clinical assessment.
title LLAMADRS: Evaluating Open-Source LLMs on Real Clinical Interviews--To Reason or Not to Reason?
topic Human-Computer Interaction
Computation and Language
I.2.7
url https://arxiv.org/abs/2501.03624