Electrokinetic Flow Modeling Through Bone Scaffold
Fuente:
arXiv
Salvato in:
| Autori principali: | , |
|---|---|
| Natura: | Preprint |
| Pubblicazione: |
2024
|
| Soggetti: | |
| Accesso online: | |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1866916555792580608 |
|---|---|
| author | Osaid, Mohammad Dasgupta, Debabrata |
| author_facet | Osaid, Mohammad Dasgupta, Debabrata |
| contents | Fluid flow and mass transfer inside a bioreactor play a pivotal role in growing bone grafts, as cell proliferation is limited by the transport of nutrients and oxygen, as well as the removal of by-products from cells within the scaffold. Traditionally, perfusion bioreactors are used for tissue-engineered bone grafts. In this study, we modeled electrokinetic flow through the graft for tissue-engineered bone grafts and compared it to pressure-driven flows. The study highlights that electrokinetic transport offers several advantages over pressure-driven flow, such as improved oxygen transport and higher shear stress. Additionally, it provides generic benefits, including greater flexibility in control mechanisms, such as easier actuation and manipulation of flow. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2501_04025 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | Electrokinetic Flow Modeling Through Bone Scaffold Osaid, Mohammad Dasgupta, Debabrata Biological Physics Fluid flow and mass transfer inside a bioreactor play a pivotal role in growing bone grafts, as cell proliferation is limited by the transport of nutrients and oxygen, as well as the removal of by-products from cells within the scaffold. Traditionally, perfusion bioreactors are used for tissue-engineered bone grafts. In this study, we modeled electrokinetic flow through the graft for tissue-engineered bone grafts and compared it to pressure-driven flows. The study highlights that electrokinetic transport offers several advantages over pressure-driven flow, such as improved oxygen transport and higher shear stress. Additionally, it provides generic benefits, including greater flexibility in control mechanisms, such as easier actuation and manipulation of flow. |
| title | Electrokinetic Flow Modeling Through Bone Scaffold |
| topic | Biological Physics |
| url | https://arxiv.org/abs/2501.04025 |