Reusable specimen-level inference in computational pathology

Fuente: arXiv
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Autores principales: Kaczmarzyk, Jakub R., Sharma, Rishul, Koo, Peter K., Saltz, Joel H.
Formato: Preprint
Publicado: 2025
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author Kaczmarzyk, Jakub R.
Sharma, Rishul
Koo, Peter K.
Saltz, Joel H.
author_facet Kaczmarzyk, Jakub R.
Sharma, Rishul
Koo, Peter K.
Saltz, Joel H.
contents Foundation models for computational pathology have shown great promise for specimen-level tasks and are increasingly accessible to researchers. However, specimen-level models built on these foundation models remain largely unavailable, hindering their broader utility and impact. To address this gap, we developed SpinPath, a toolkit designed to democratize specimen-level deep learning by providing a zoo of pretrained specimen-level models, a Python-based inference engine, and a JavaScript-based inference platform. We demonstrate the utility of SpinPath in metastasis detection tasks across nine foundation models. SpinPath may foster reproducibility, simplify experimentation, and accelerate the adoption of specimen-level deep learning in computational pathology research.
format Preprint
id arxiv_https___arxiv_org_abs_2501_05945
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Reusable specimen-level inference in computational pathology
Kaczmarzyk, Jakub R.
Sharma, Rishul
Koo, Peter K.
Saltz, Joel H.
Image and Video Processing
Computer Vision and Pattern Recognition
Tissues and Organs
Foundation models for computational pathology have shown great promise for specimen-level tasks and are increasingly accessible to researchers. However, specimen-level models built on these foundation models remain largely unavailable, hindering their broader utility and impact. To address this gap, we developed SpinPath, a toolkit designed to democratize specimen-level deep learning by providing a zoo of pretrained specimen-level models, a Python-based inference engine, and a JavaScript-based inference platform. We demonstrate the utility of SpinPath in metastasis detection tasks across nine foundation models. SpinPath may foster reproducibility, simplify experimentation, and accelerate the adoption of specimen-level deep learning in computational pathology research.
title Reusable specimen-level inference in computational pathology
topic Image and Video Processing
Computer Vision and Pattern Recognition
Tissues and Organs
url https://arxiv.org/abs/2501.05945