ML-assisted Randomization Tests for Detecting Treatment Effects in A/B Experiments

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Hauptverfasser: Guo, Wenxuan, Lee, JungHo, Toulis, Panos
Format: Preprint
Veröffentlicht: 2025
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author Guo, Wenxuan
Lee, JungHo
Toulis, Panos
author_facet Guo, Wenxuan
Lee, JungHo
Toulis, Panos
contents Experimentation is widely utilized for causal inference and data-driven decision-making across disciplines. In an A/B experiment, for example, an online business randomizes two different treatments (e.g., website designs) to their customers and then aims to infer which treatment is better. In this paper, we construct randomization tests for complex treatment effects, including heterogeneity and interference. A key feature of our approach is the use of flexible machine learning (ML) models, where the test statistic is defined as the difference between the cross-validation errors from two ML models, one including the treatment variable and the other without it. This approach combines the predictive power of modern ML tools with the finite-sample validity of randomization procedures, enabling a robust and efficient way to detect complex treatment effects in experimental settings. We demonstrate this combined benefit both theoretically and empirically through applied examples.
format Preprint
id arxiv_https___arxiv_org_abs_2501_07722
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle ML-assisted Randomization Tests for Detecting Treatment Effects in A/B Experiments
Guo, Wenxuan
Lee, JungHo
Toulis, Panos
Methodology
Machine Learning
Experimentation is widely utilized for causal inference and data-driven decision-making across disciplines. In an A/B experiment, for example, an online business randomizes two different treatments (e.g., website designs) to their customers and then aims to infer which treatment is better. In this paper, we construct randomization tests for complex treatment effects, including heterogeneity and interference. A key feature of our approach is the use of flexible machine learning (ML) models, where the test statistic is defined as the difference between the cross-validation errors from two ML models, one including the treatment variable and the other without it. This approach combines the predictive power of modern ML tools with the finite-sample validity of randomization procedures, enabling a robust and efficient way to detect complex treatment effects in experimental settings. We demonstrate this combined benefit both theoretically and empirically through applied examples.
title ML-assisted Randomization Tests for Detecting Treatment Effects in A/B Experiments
topic Methodology
Machine Learning
url https://arxiv.org/abs/2501.07722