An Open Source Validation System for Continuous Arterial Blood Pressure Measuring Sensors

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Main Authors: Répai, Attila, Földi, Sándor, Sótonyi, Péter, Cserey, György
Format: Preprint
Published: 2025
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author Répai, Attila
Földi, Sándor
Sótonyi, Péter
Cserey, György
author_facet Répai, Attila
Földi, Sándor
Sótonyi, Péter
Cserey, György
contents Measuring the blood pressure waveform is becoming a more frequently studied area. The development of sensor technologies opens many new ways to be able to measure high-quality signals. The development of such an aim-specific sensor can be time-consuming, expensive, and difficult to test or validate with known and consistent waveforms. In this paper, we present an open source blood pressure waveform simulator with an open source Python validation package to reduce development costs for early-stage sensor development and research. The simulator mainly consists of 3D printed parts which technology has become a widely available and cheap solution. The core part of the simulator is a 3D printed cam that can be generated based on real blood pressure waveforms. The validation framework can create a detailed comparison between the signal waveform used to design the cam and the measured time series from the sensor being validated. The presented simulator proved to be robust and accurate in short- and long-term use, as it produced the signal waveform consistently and accurately. To validate this solution, a 3D force sensor was used, which was proven earlier to be able to measure high-quality blood pressure waveforms on the radial artery at the wrist. The results showed high similarity between the measured and the nominal waveforms, meaning that comparing the normalized signals, the RMSE value ranged from $0.0276 \pm 0.0047$ to $0.0212 \pm 0.0023$, and the Pearson correlation ranged from $0.9933 \pm 0.0027$ to $0.9978 \pm 0.0005$. Our validation framework is available at https://github.com/repat8/cam-bpw-sim. Our hardware framework, which allows reproduction of the presented solution, is available at https://github.com/repat8/cam-bpw-sim-hardware. The entire design is an open source project and was developed using free software.
format Preprint
id arxiv_https___arxiv_org_abs_2501_07973
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle An Open Source Validation System for Continuous Arterial Blood Pressure Measuring Sensors
Répai, Attila
Földi, Sándor
Sótonyi, Péter
Cserey, György
Medical Physics
Systems and Control
Measuring the blood pressure waveform is becoming a more frequently studied area. The development of sensor technologies opens many new ways to be able to measure high-quality signals. The development of such an aim-specific sensor can be time-consuming, expensive, and difficult to test or validate with known and consistent waveforms. In this paper, we present an open source blood pressure waveform simulator with an open source Python validation package to reduce development costs for early-stage sensor development and research. The simulator mainly consists of 3D printed parts which technology has become a widely available and cheap solution. The core part of the simulator is a 3D printed cam that can be generated based on real blood pressure waveforms. The validation framework can create a detailed comparison between the signal waveform used to design the cam and the measured time series from the sensor being validated. The presented simulator proved to be robust and accurate in short- and long-term use, as it produced the signal waveform consistently and accurately. To validate this solution, a 3D force sensor was used, which was proven earlier to be able to measure high-quality blood pressure waveforms on the radial artery at the wrist. The results showed high similarity between the measured and the nominal waveforms, meaning that comparing the normalized signals, the RMSE value ranged from $0.0276 \pm 0.0047$ to $0.0212 \pm 0.0023$, and the Pearson correlation ranged from $0.9933 \pm 0.0027$ to $0.9978 \pm 0.0005$. Our validation framework is available at https://github.com/repat8/cam-bpw-sim. Our hardware framework, which allows reproduction of the presented solution, is available at https://github.com/repat8/cam-bpw-sim-hardware. The entire design is an open source project and was developed using free software.
title An Open Source Validation System for Continuous Arterial Blood Pressure Measuring Sensors
topic Medical Physics
Systems and Control
url https://arxiv.org/abs/2501.07973