Combining imaging and shape features for prediction tasks of Alzheimer's disease classification and brain age regression

Fuente: arXiv
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Autores principales: Shehata, Nairouz, Piçarra, Carolina, Glocker, Ben
Formato: Preprint
Publicado: 2025
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author Shehata, Nairouz
Piçarra, Carolina
Glocker, Ben
author_facet Shehata, Nairouz
Piçarra, Carolina
Glocker, Ben
contents We investigate combining imaging and shape features extracted from MRI for the clinically relevant tasks of brain age prediction and Alzheimer's disease classification. Our proposed model fuses ResNet-extracted image embeddings with shape embeddings from a bespoke graph neural network. The shape embeddings are derived from surface meshes of 15 brain structures, capturing detailed geometric information. Combined with the appearance features from T1-weighted images, we observe improvements in the prediction performance on both tasks, with substantial gains for classification. We evaluate the model using public datasets, including CamCAN, IXI, and OASIS3, demonstrating the effectiveness of fusing imaging and shape features for brain analysis.
format Preprint
id arxiv_https___arxiv_org_abs_2501_07994
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Combining imaging and shape features for prediction tasks of Alzheimer's disease classification and brain age regression
Shehata, Nairouz
Piçarra, Carolina
Glocker, Ben
Computer Vision and Pattern Recognition
Machine Learning
Image and Video Processing
We investigate combining imaging and shape features extracted from MRI for the clinically relevant tasks of brain age prediction and Alzheimer's disease classification. Our proposed model fuses ResNet-extracted image embeddings with shape embeddings from a bespoke graph neural network. The shape embeddings are derived from surface meshes of 15 brain structures, capturing detailed geometric information. Combined with the appearance features from T1-weighted images, we observe improvements in the prediction performance on both tasks, with substantial gains for classification. We evaluate the model using public datasets, including CamCAN, IXI, and OASIS3, demonstrating the effectiveness of fusing imaging and shape features for brain analysis.
title Combining imaging and shape features for prediction tasks of Alzheimer's disease classification and brain age regression
topic Computer Vision and Pattern Recognition
Machine Learning
Image and Video Processing
url https://arxiv.org/abs/2501.07994