CoronaryHemodynamics: An Automated Simulation Framework for Coronary Artery Hemodynamics Using OpenFOAM

Fuente: arXiv
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Autori principali: Mao, Yijin, Zhang, Yuwen
Natura: Preprint
Pubblicazione: 2025
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author Mao, Yijin
Zhang, Yuwen
author_facet Mao, Yijin
Zhang, Yuwen
contents CoronaryHemodynamics is a comprehensive simulation package developed on the OpenFOAM platform, designed specifically for coronary artery hemodynamics analysis. The package integrates a complete suite of tools for simulation preparation, including automatic case setup, boundary condition configuration, computational domain meshing, and a CFD solver. It fully supports MPI parallelization, leveraging the native parallel computing capabilities of OpenFOAM. The package implements Windkessel boundary conditions at the aorta outlet and all coronary vessel outlets, with outlet parameters automatically derived from physiological metrics such as heart rate, systolic blood pressure, and myocardial volume. At the aorta inlet, a parabolic flow profile is applied based on the input flow rate waveform. CoronaryHemodynamics supports both steady-state and transient solvers, enabling the simulation of various flow conditions. Flow rate and pressure data are recorded at all boundaries during the simulation, and outputs such as wall shear stress, pressure fields, and velocity fields are automatically stored for detailed post-processing and analysis. By automating critical aspects of the simulation pipeline and integrating physiological boundary conditions, CoronaryHemodynamics offers an efficient and robust framework to study coronary hemodynamics in both research and clinical applications. The package can be found at https://github.com/alundilong/CoronaryHemodynamics.
format Preprint
id arxiv_https___arxiv_org_abs_2501_08340
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle CoronaryHemodynamics: An Automated Simulation Framework for Coronary Artery Hemodynamics Using OpenFOAM
Mao, Yijin
Zhang, Yuwen
Fluid Dynamics
CoronaryHemodynamics is a comprehensive simulation package developed on the OpenFOAM platform, designed specifically for coronary artery hemodynamics analysis. The package integrates a complete suite of tools for simulation preparation, including automatic case setup, boundary condition configuration, computational domain meshing, and a CFD solver. It fully supports MPI parallelization, leveraging the native parallel computing capabilities of OpenFOAM. The package implements Windkessel boundary conditions at the aorta outlet and all coronary vessel outlets, with outlet parameters automatically derived from physiological metrics such as heart rate, systolic blood pressure, and myocardial volume. At the aorta inlet, a parabolic flow profile is applied based on the input flow rate waveform. CoronaryHemodynamics supports both steady-state and transient solvers, enabling the simulation of various flow conditions. Flow rate and pressure data are recorded at all boundaries during the simulation, and outputs such as wall shear stress, pressure fields, and velocity fields are automatically stored for detailed post-processing and analysis. By automating critical aspects of the simulation pipeline and integrating physiological boundary conditions, CoronaryHemodynamics offers an efficient and robust framework to study coronary hemodynamics in both research and clinical applications. The package can be found at https://github.com/alundilong/CoronaryHemodynamics.
title CoronaryHemodynamics: An Automated Simulation Framework for Coronary Artery Hemodynamics Using OpenFOAM
topic Fluid Dynamics
url https://arxiv.org/abs/2501.08340