The sleeping bacterium: shedding light on the resuscitation mechanism

Fuente: arXiv
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Autores principales: Alfinito, Eleonora, Beccaria, Matteo
Formato: Preprint
Publicado: 2025
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author Alfinito, Eleonora
Beccaria, Matteo
author_facet Alfinito, Eleonora
Beccaria, Matteo
contents The revival mechanism in dormant bacteria is a puzzling and open issue. We propose a model of information diffusion on a regular grid where agents represent bacteria and their mutual interactions implement quorum sensing. Agents may have different metabolic characteristics corresponding to multiple phenotypes. The intra/inter phenotype cooperation is analyzed under different metabolic and productivity conditions. We study the interactions between rapidly reproducing active bacteria and non-reproducing quiescent bacteria. We highlight the conditions under which the quiescent bacteria may revive. The occurrence of revival is generally related to a change in environmental conditions. Our results support this picture showing that revival can be mediated by the presence of different catalyst bacteria that produce the necessary resources .
format Preprint
id arxiv_https___arxiv_org_abs_2501_09366
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle The sleeping bacterium: shedding light on the resuscitation mechanism
Alfinito, Eleonora
Beccaria, Matteo
Biological Physics
The revival mechanism in dormant bacteria is a puzzling and open issue. We propose a model of information diffusion on a regular grid where agents represent bacteria and their mutual interactions implement quorum sensing. Agents may have different metabolic characteristics corresponding to multiple phenotypes. The intra/inter phenotype cooperation is analyzed under different metabolic and productivity conditions. We study the interactions between rapidly reproducing active bacteria and non-reproducing quiescent bacteria. We highlight the conditions under which the quiescent bacteria may revive. The occurrence of revival is generally related to a change in environmental conditions. Our results support this picture showing that revival can be mediated by the presence of different catalyst bacteria that produce the necessary resources .
title The sleeping bacterium: shedding light on the resuscitation mechanism
topic Biological Physics
url https://arxiv.org/abs/2501.09366