Biomedical Knowledge Graph: A Survey of Domains, Tasks, and Real-World Applications

Fuente: arXiv
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Autori principali: Lu, Yuxing, Goi, Sin Yee, Zhao, Xukai, Wang, Jinzhuo
Natura: Preprint
Pubblicazione: 2025
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author Lu, Yuxing
Goi, Sin Yee
Zhao, Xukai
Wang, Jinzhuo
author_facet Lu, Yuxing
Goi, Sin Yee
Zhao, Xukai
Wang, Jinzhuo
contents Biomedical knowledge graphs (BKGs) have emerged as powerful tools for organizing and leveraging the vast and complex data found across the biomedical field. Yet, current reviews of BKGs often limit their scope to specific domains or methods, overlooking the broader landscape and the rapid technological progress reshaping it. In this survey, we address this gap by offering a systematic review of BKGs from three core perspectives: domains, tasks, and applications. We begin by examining how BKGs are constructed from diverse data sources, including molecular interactions, pharmacological datasets, and clinical records. Next, we discuss the essential tasks enabled by BKGs, focusing on knowledge management, retrieval, reasoning, and interpretation. Finally, we highlight real-world applications in precision medicine, drug discovery, and scientific research, illustrating the translational impact of BKGs across multiple sectors. By synthesizing these perspectives into a unified framework, this survey not only clarifies the current state of BKG research but also establishes a foundation for future exploration, enabling both innovative methodological advances and practical implementations.
format Preprint
id arxiv_https___arxiv_org_abs_2501_11632
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Biomedical Knowledge Graph: A Survey of Domains, Tasks, and Real-World Applications
Lu, Yuxing
Goi, Sin Yee
Zhao, Xukai
Wang, Jinzhuo
Computation and Language
Artificial Intelligence
Computational Engineering, Finance, and Science
Information Retrieval
Biomedical knowledge graphs (BKGs) have emerged as powerful tools for organizing and leveraging the vast and complex data found across the biomedical field. Yet, current reviews of BKGs often limit their scope to specific domains or methods, overlooking the broader landscape and the rapid technological progress reshaping it. In this survey, we address this gap by offering a systematic review of BKGs from three core perspectives: domains, tasks, and applications. We begin by examining how BKGs are constructed from diverse data sources, including molecular interactions, pharmacological datasets, and clinical records. Next, we discuss the essential tasks enabled by BKGs, focusing on knowledge management, retrieval, reasoning, and interpretation. Finally, we highlight real-world applications in precision medicine, drug discovery, and scientific research, illustrating the translational impact of BKGs across multiple sectors. By synthesizing these perspectives into a unified framework, this survey not only clarifies the current state of BKG research but also establishes a foundation for future exploration, enabling both innovative methodological advances and practical implementations.
title Biomedical Knowledge Graph: A Survey of Domains, Tasks, and Real-World Applications
topic Computation and Language
Artificial Intelligence
Computational Engineering, Finance, and Science
Information Retrieval
url https://arxiv.org/abs/2501.11632