MyDigiTwin: A Privacy-Preserving Framework for Personalized Cardiovascular Risk Prediction and Scenario Exploration

Fuente: arXiv
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Autores principales: Cadavid, Héctor, Mo, Hyunho, Arends, Bauke, Dziopa, Katarzyna, Bron, Esther E., Bos, Daniel, Georgievska, Sonja, van der Harst, Pim
Formato: Preprint
Publicado: 2025
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author Cadavid, Héctor
Mo, Hyunho
Arends, Bauke
Dziopa, Katarzyna
Bron, Esther E.
Bos, Daniel
Georgievska, Sonja
van der Harst, Pim
author_facet Cadavid, Héctor
Mo, Hyunho
Arends, Bauke
Dziopa, Katarzyna
Bron, Esther E.
Bos, Daniel
Georgievska, Sonja
van der Harst, Pim
contents Cardiovascular disease (CVD) remains a leading cause of death, and primary prevention through personalized interventions is crucial. This paper introduces MyDigiTwin, a framework that integrates health digital twins with personal health environments to empower patients in exploring personalized health scenarios while ensuring data privacy. MyDigiTwin uses federated learning to train predictive models across distributed datasets without transferring raw data, and a novel data harmonization framework addresses semantic and format inconsistencies in health data. A proof-of-concept demonstrates the feasibility of harmonizing and using cohort data to train privacy-preserving CVD prediction models. This framework offers a scalable solution for proactive, personalized cardiovascular care and sets the stage for future applications in real-world healthcare settings.
format Preprint
id arxiv_https___arxiv_org_abs_2501_12193
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle MyDigiTwin: A Privacy-Preserving Framework for Personalized Cardiovascular Risk Prediction and Scenario Exploration
Cadavid, Héctor
Mo, Hyunho
Arends, Bauke
Dziopa, Katarzyna
Bron, Esther E.
Bos, Daniel
Georgievska, Sonja
van der Harst, Pim
Machine Learning
Human-Computer Interaction
Cardiovascular disease (CVD) remains a leading cause of death, and primary prevention through personalized interventions is crucial. This paper introduces MyDigiTwin, a framework that integrates health digital twins with personal health environments to empower patients in exploring personalized health scenarios while ensuring data privacy. MyDigiTwin uses federated learning to train predictive models across distributed datasets without transferring raw data, and a novel data harmonization framework addresses semantic and format inconsistencies in health data. A proof-of-concept demonstrates the feasibility of harmonizing and using cohort data to train privacy-preserving CVD prediction models. This framework offers a scalable solution for proactive, personalized cardiovascular care and sets the stage for future applications in real-world healthcare settings.
title MyDigiTwin: A Privacy-Preserving Framework for Personalized Cardiovascular Risk Prediction and Scenario Exploration
topic Machine Learning
Human-Computer Interaction
url https://arxiv.org/abs/2501.12193