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Main Authors: Wu, Chenxu, Kong, Qingpeng, Jiang, Zihang, Zhou, S. Kevin
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2501.13514
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author Wu, Chenxu
Kong, Qingpeng
Jiang, Zihang
Zhou, S. Kevin
author_facet Wu, Chenxu
Kong, Qingpeng
Jiang, Zihang
Zhou, S. Kevin
contents Magnetic Resonance Imaging (MRI), including diffusion MRI (dMRI), serves as a ``microscope'' for anatomical structures and routinely mitigates the influence of low signal-to-noise ratio scans by compromising temporal or spatial resolution. However, these compromises fail to meet clinical demands for both efficiency and precision. Consequently, denoising is a vital preprocessing step, particularly for dMRI, where clean data is unavailable. In this paper, we introduce Di-Fusion, a fully self-supervised denoising method that leverages the latter diffusion steps and an adaptive sampling process. Unlike previous approaches, our single-stage framework achieves efficient and stable training without extra noise model training and offers adaptive and controllable results in the sampling process. Our thorough experiments on real and simulated data demonstrate that Di-Fusion achieves state-of-the-art performance in microstructure modeling, tractography tracking, and other downstream tasks. Code is available at https://github.com/FouierL/Di-Fusion.
format Preprint
id arxiv_https___arxiv_org_abs_2501_13514
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Self-Supervised Diffusion MRI Denoising via Iterative and Stable Refinement
Wu, Chenxu
Kong, Qingpeng
Jiang, Zihang
Zhou, S. Kevin
Image and Video Processing
Computer Vision and Pattern Recognition
Magnetic Resonance Imaging (MRI), including diffusion MRI (dMRI), serves as a ``microscope'' for anatomical structures and routinely mitigates the influence of low signal-to-noise ratio scans by compromising temporal or spatial resolution. However, these compromises fail to meet clinical demands for both efficiency and precision. Consequently, denoising is a vital preprocessing step, particularly for dMRI, where clean data is unavailable. In this paper, we introduce Di-Fusion, a fully self-supervised denoising method that leverages the latter diffusion steps and an adaptive sampling process. Unlike previous approaches, our single-stage framework achieves efficient and stable training without extra noise model training and offers adaptive and controllable results in the sampling process. Our thorough experiments on real and simulated data demonstrate that Di-Fusion achieves state-of-the-art performance in microstructure modeling, tractography tracking, and other downstream tasks. Code is available at https://github.com/FouierL/Di-Fusion.
title Self-Supervised Diffusion MRI Denoising via Iterative and Stable Refinement
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2501.13514