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Hauptverfasser: Blot, Vincent, de Brionne, Alexandra Lorenzo, Sellami, Ines, Trassard, Olivier, Beau, Isabelle, Sonigo, Charlotte, Brunel, Nicolas J-B.
Format: Preprint
Veröffentlicht: 2025
Schlagworte:
Online-Zugang:https://arxiv.org/abs/2501.14036
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author Blot, Vincent
de Brionne, Alexandra Lorenzo
Sellami, Ines
Trassard, Olivier
Beau, Isabelle
Sonigo, Charlotte
Brunel, Nicolas J-B.
author_facet Blot, Vincent
de Brionne, Alexandra Lorenzo
Sellami, Ines
Trassard, Olivier
Beau, Isabelle
Sonigo, Charlotte
Brunel, Nicolas J-B.
contents Image analysis is a key tool for describing the detailed mechanisms of folliculogenesis, such as evaluating the quantity of mouse Primordial ovarian Follicles (PMF) in the ovarian reserve. The development of high-resolution virtual slide scanners offers the possibility of quantifying, robustifying and accelerating the histopathological procedure. A major challenge for machine learning is to control the precision of predictions while enabling a high recall, in order to provide reproducibility. We use a multiple testing procedure that gives an overperforming way to solve the standard Precision-Recall trade-off that gives probabilistic guarantees on the precision. In addition, we significantly improve the overall performance of the models (increase of F1-score) by selecting the decision threshold using contextual biological information or using an auxiliary model. As it is model-agnostic, this contextual selection procedure paves the way to the development of a strategy that can improve the performance of any model without the need of retraining it.
format Preprint
id arxiv_https___arxiv_org_abs_2501_14036
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Efficient Precision Control in Object Detection Models for Enhanced and Reliable Ovarian Follicle Counting
Blot, Vincent
de Brionne, Alexandra Lorenzo
Sellami, Ines
Trassard, Olivier
Beau, Isabelle
Sonigo, Charlotte
Brunel, Nicolas J-B.
Machine Learning
Image analysis is a key tool for describing the detailed mechanisms of folliculogenesis, such as evaluating the quantity of mouse Primordial ovarian Follicles (PMF) in the ovarian reserve. The development of high-resolution virtual slide scanners offers the possibility of quantifying, robustifying and accelerating the histopathological procedure. A major challenge for machine learning is to control the precision of predictions while enabling a high recall, in order to provide reproducibility. We use a multiple testing procedure that gives an overperforming way to solve the standard Precision-Recall trade-off that gives probabilistic guarantees on the precision. In addition, we significantly improve the overall performance of the models (increase of F1-score) by selecting the decision threshold using contextual biological information or using an auxiliary model. As it is model-agnostic, this contextual selection procedure paves the way to the development of a strategy that can improve the performance of any model without the need of retraining it.
title Efficient Precision Control in Object Detection Models for Enhanced and Reliable Ovarian Follicle Counting
topic Machine Learning
url https://arxiv.org/abs/2501.14036