Brain-Adapter: Enhancing Neurological Disorder Analysis with Adapter-Tuning Multimodal Large Language Models

Fuente: arXiv
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Auteurs principaux: Zhang, Jing, Yu, Xiaowei, Lyu, Yanjun, Zhang, Lu, Chen, Tong, Cao, Chao, Zhuang, Yan, Chen, Minheng, Liu, Tianming, Zhu, Dajiang
Format: Preprint
Publié: 2025
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author Zhang, Jing
Yu, Xiaowei
Lyu, Yanjun
Zhang, Lu
Chen, Tong
Cao, Chao
Zhuang, Yan
Chen, Minheng
Liu, Tianming
Zhu, Dajiang
author_facet Zhang, Jing
Yu, Xiaowei
Lyu, Yanjun
Zhang, Lu
Chen, Tong
Cao, Chao
Zhuang, Yan
Chen, Minheng
Liu, Tianming
Zhu, Dajiang
contents Understanding brain disorders is crucial for accurate clinical diagnosis and treatment. Recent advances in Multimodal Large Language Models (MLLMs) offer a promising approach to interpreting medical images with the support of text descriptions. However, previous research has primarily focused on 2D medical images, leaving richer spatial information of 3D images under-explored, and single-modality-based methods are limited by overlooking the critical clinical information contained in other modalities. To address this issue, this paper proposes Brain-Adapter, a novel approach that incorporates an extra bottleneck layer to learn new knowledge and instill it into the original pre-trained knowledge. The major idea is to incorporate a lightweight bottleneck layer to train fewer parameters while capturing essential information and utilize a Contrastive Language-Image Pre-training (CLIP) strategy to align multimodal data within a unified representation space. Extensive experiments demonstrated the effectiveness of our approach in integrating multimodal data to significantly improve the diagnosis accuracy without high computational costs, highlighting the potential to enhance real-world diagnostic workflows.
format Preprint
id arxiv_https___arxiv_org_abs_2501_16282
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Brain-Adapter: Enhancing Neurological Disorder Analysis with Adapter-Tuning Multimodal Large Language Models
Zhang, Jing
Yu, Xiaowei
Lyu, Yanjun
Zhang, Lu
Chen, Tong
Cao, Chao
Zhuang, Yan
Chen, Minheng
Liu, Tianming
Zhu, Dajiang
Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
Understanding brain disorders is crucial for accurate clinical diagnosis and treatment. Recent advances in Multimodal Large Language Models (MLLMs) offer a promising approach to interpreting medical images with the support of text descriptions. However, previous research has primarily focused on 2D medical images, leaving richer spatial information of 3D images under-explored, and single-modality-based methods are limited by overlooking the critical clinical information contained in other modalities. To address this issue, this paper proposes Brain-Adapter, a novel approach that incorporates an extra bottleneck layer to learn new knowledge and instill it into the original pre-trained knowledge. The major idea is to incorporate a lightweight bottleneck layer to train fewer parameters while capturing essential information and utilize a Contrastive Language-Image Pre-training (CLIP) strategy to align multimodal data within a unified representation space. Extensive experiments demonstrated the effectiveness of our approach in integrating multimodal data to significantly improve the diagnosis accuracy without high computational costs, highlighting the potential to enhance real-world diagnostic workflows.
title Brain-Adapter: Enhancing Neurological Disorder Analysis with Adapter-Tuning Multimodal Large Language Models
topic Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2501.16282