VeriFact: Verifying Facts in LLM-Generated Clinical Text with Electronic Health Records

Fuente: arXiv
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Autori principali: Chung, Philip, Swaminathan, Akshay, Goodell, Alex J., Kim, Yeasul, Reincke, S. Momsen, Han, Lichy, Deverett, Ben, Sadeghi, Mohammad Amin, Ariss, Abdel-Badih, Ghanem, Marc, Seong, David, Lee, Andrew A., Coombes, Caitlin E., Bradshaw, Brad, Sufian, Mahir A., Hong, Hyo Jung, Nguyen, Teresa P., Rasouli, Mohammad R., Kamra, Komal, Burbridge, Mark A., McAvoy, James C., Saffary, Roya, Ma, Stephen P., Dash, Dev, Xie, James, Wang, Ellen Y., Schmiesing, Clifford A., Shah, Nigam, Aghaeepour, Nima
Natura: Preprint
Pubblicazione: 2025
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author Chung, Philip
Swaminathan, Akshay
Goodell, Alex J.
Kim, Yeasul
Reincke, S. Momsen
Han, Lichy
Deverett, Ben
Sadeghi, Mohammad Amin
Ariss, Abdel-Badih
Ghanem, Marc
Seong, David
Lee, Andrew A.
Coombes, Caitlin E.
Bradshaw, Brad
Sufian, Mahir A.
Hong, Hyo Jung
Nguyen, Teresa P.
Rasouli, Mohammad R.
Kamra, Komal
Burbridge, Mark A.
McAvoy, James C.
Saffary, Roya
Ma, Stephen P.
Dash, Dev
Xie, James
Wang, Ellen Y.
Schmiesing, Clifford A.
Shah, Nigam
Aghaeepour, Nima
author_facet Chung, Philip
Swaminathan, Akshay
Goodell, Alex J.
Kim, Yeasul
Reincke, S. Momsen
Han, Lichy
Deverett, Ben
Sadeghi, Mohammad Amin
Ariss, Abdel-Badih
Ghanem, Marc
Seong, David
Lee, Andrew A.
Coombes, Caitlin E.
Bradshaw, Brad
Sufian, Mahir A.
Hong, Hyo Jung
Nguyen, Teresa P.
Rasouli, Mohammad R.
Kamra, Komal
Burbridge, Mark A.
McAvoy, James C.
Saffary, Roya
Ma, Stephen P.
Dash, Dev
Xie, James
Wang, Ellen Y.
Schmiesing, Clifford A.
Shah, Nigam
Aghaeepour, Nima
contents Methods to ensure factual accuracy of text generated by large language models (LLM) in clinical medicine are lacking. VeriFact is an artificial intelligence system that combines retrieval-augmented generation and LLM-as-a-Judge to verify whether LLM-generated text is factually supported by a patient's medical history based on their electronic health record (EHR). To evaluate this system, we introduce VeriFact-BHC, a new dataset that decomposes Brief Hospital Course narratives from discharge summaries into a set of simple statements with clinician annotations for whether each statement is supported by the patient's EHR clinical notes. Whereas highest agreement between clinicians was 88.5%, VeriFact achieves up to 92.7% agreement when compared to a denoised and adjudicated average human clinican ground truth, suggesting that VeriFact exceeds the average clinician's ability to fact-check text against a patient's medical record. VeriFact may accelerate the development of LLM-based EHR applications by removing current evaluation bottlenecks.
format Preprint
id arxiv_https___arxiv_org_abs_2501_16672
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle VeriFact: Verifying Facts in LLM-Generated Clinical Text with Electronic Health Records
Chung, Philip
Swaminathan, Akshay
Goodell, Alex J.
Kim, Yeasul
Reincke, S. Momsen
Han, Lichy
Deverett, Ben
Sadeghi, Mohammad Amin
Ariss, Abdel-Badih
Ghanem, Marc
Seong, David
Lee, Andrew A.
Coombes, Caitlin E.
Bradshaw, Brad
Sufian, Mahir A.
Hong, Hyo Jung
Nguyen, Teresa P.
Rasouli, Mohammad R.
Kamra, Komal
Burbridge, Mark A.
McAvoy, James C.
Saffary, Roya
Ma, Stephen P.
Dash, Dev
Xie, James
Wang, Ellen Y.
Schmiesing, Clifford A.
Shah, Nigam
Aghaeepour, Nima
Artificial Intelligence
Computation and Language
Information Retrieval
Logic in Computer Science
Methods to ensure factual accuracy of text generated by large language models (LLM) in clinical medicine are lacking. VeriFact is an artificial intelligence system that combines retrieval-augmented generation and LLM-as-a-Judge to verify whether LLM-generated text is factually supported by a patient's medical history based on their electronic health record (EHR). To evaluate this system, we introduce VeriFact-BHC, a new dataset that decomposes Brief Hospital Course narratives from discharge summaries into a set of simple statements with clinician annotations for whether each statement is supported by the patient's EHR clinical notes. Whereas highest agreement between clinicians was 88.5%, VeriFact achieves up to 92.7% agreement when compared to a denoised and adjudicated average human clinican ground truth, suggesting that VeriFact exceeds the average clinician's ability to fact-check text against a patient's medical record. VeriFact may accelerate the development of LLM-based EHR applications by removing current evaluation bottlenecks.
title VeriFact: Verifying Facts in LLM-Generated Clinical Text with Electronic Health Records
topic Artificial Intelligence
Computation and Language
Information Retrieval
Logic in Computer Science
url https://arxiv.org/abs/2501.16672