Explainability and AI Confidence in Clinical Decision Support Systems: Effects on Trust, Diagnostic Performance, and Cognitive Load in Breast Cancer Care

Fuente: arXiv
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Autores principales: Rezaeian, Olya, Bayrak, Alparslan Emrah, Asan, Onur
Formato: Preprint
Publicado: 2025
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author Rezaeian, Olya
Bayrak, Alparslan Emrah
Asan, Onur
author_facet Rezaeian, Olya
Bayrak, Alparslan Emrah
Asan, Onur
contents Artificial Intelligence (AI) has demonstrated potential in healthcare, particularly in enhancing diagnostic accuracy and decision-making through Clinical Decision Support Systems (CDSSs). However, the successful implementation of these systems relies on user trust and reliance, which can be influenced by explainable AI. This study explores the impact of varying explainability levels on clinicians trust, cognitive load, and diagnostic performance in breast cancer detection. Utilizing an interrupted time series design, we conducted a web-based experiment involving 28 healthcare professionals. The results revealed that high confidence scores substantially increased trust but also led to overreliance, reducing diagnostic accuracy. In contrast, low confidence scores decreased trust and agreement while increasing diagnosis duration, reflecting more cautious behavior. Some explainability features influenced cognitive load by increasing stress levels. Additionally, demographic factors such as age, gender, and professional role shaped participants' perceptions and interactions with the system. This study provides valuable insights into how explainability impact clinicians' behavior and decision-making. The findings highlight the importance of designing AI-driven CDSSs that balance transparency, usability, and cognitive demands to foster trust and improve integration into clinical workflows.
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id arxiv_https___arxiv_org_abs_2501_16693
institution arXiv
publishDate 2025
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spellingShingle Explainability and AI Confidence in Clinical Decision Support Systems: Effects on Trust, Diagnostic Performance, and Cognitive Load in Breast Cancer Care
Rezaeian, Olya
Bayrak, Alparslan Emrah
Asan, Onur
Human-Computer Interaction
Artificial Intelligence (AI) has demonstrated potential in healthcare, particularly in enhancing diagnostic accuracy and decision-making through Clinical Decision Support Systems (CDSSs). However, the successful implementation of these systems relies on user trust and reliance, which can be influenced by explainable AI. This study explores the impact of varying explainability levels on clinicians trust, cognitive load, and diagnostic performance in breast cancer detection. Utilizing an interrupted time series design, we conducted a web-based experiment involving 28 healthcare professionals. The results revealed that high confidence scores substantially increased trust but also led to overreliance, reducing diagnostic accuracy. In contrast, low confidence scores decreased trust and agreement while increasing diagnosis duration, reflecting more cautious behavior. Some explainability features influenced cognitive load by increasing stress levels. Additionally, demographic factors such as age, gender, and professional role shaped participants' perceptions and interactions with the system. This study provides valuable insights into how explainability impact clinicians' behavior and decision-making. The findings highlight the importance of designing AI-driven CDSSs that balance transparency, usability, and cognitive demands to foster trust and improve integration into clinical workflows.
title Explainability and AI Confidence in Clinical Decision Support Systems: Effects on Trust, Diagnostic Performance, and Cognitive Load in Breast Cancer Care
topic Human-Computer Interaction
url https://arxiv.org/abs/2501.16693