Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Preprint |
| Published: |
2025
|
| Subjects: | |
| Online Access: | https://arxiv.org/abs/2501.16959 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1866912207363637248 |
|---|---|
| author | Lu, Estelle Cisternas, Williams Flores Uhl, Héloïse Chargueraud, Alexandre Grimal, Quentin Renaud, Guillaume Minonzio, Jean-Gabriel Fattaccioli, Jacques |
| author_facet | Lu, Estelle Cisternas, Williams Flores Uhl, Héloïse Chargueraud, Alexandre Grimal, Quentin Renaud, Guillaume Minonzio, Jean-Gabriel Fattaccioli, Jacques |
| contents | Blood-mimicking fluids (BMFs) play a critical role in ultrasonic imaging and Doppler flow studies by replicating the physical and acoustic properties of blood. This study introduces a novel soybean oil-in-water emulsion as a BMF with particle size and deformability akin to red blood cells. Using a millifluidic device, we cross-validated flow profiles through both Doppler velocimetry and optical particle tracking, demonstrating compatibility with theoretical Poiseuille flow models. The millifluidic chip, fabricated via stereolithography, provided an optimized platform for dual optical and ultrasonic assessments. Results showed strong agreement between the two methods across a range of flow rates, affirming the suitability of the emulsion for velocimetry applications. Furthermore, the acoustic properties of soybean oil droplets support their potential as an echogenic and stable alternative to conventional BMFs. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2501_16959 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | Assessing ultrasonic and optical flow velocimetry in a millifluidic device using oil-in-water emulsions as blood mimicking fluid Lu, Estelle Cisternas, Williams Flores Uhl, Héloïse Chargueraud, Alexandre Grimal, Quentin Renaud, Guillaume Minonzio, Jean-Gabriel Fattaccioli, Jacques Medical Physics Blood-mimicking fluids (BMFs) play a critical role in ultrasonic imaging and Doppler flow studies by replicating the physical and acoustic properties of blood. This study introduces a novel soybean oil-in-water emulsion as a BMF with particle size and deformability akin to red blood cells. Using a millifluidic device, we cross-validated flow profiles through both Doppler velocimetry and optical particle tracking, demonstrating compatibility with theoretical Poiseuille flow models. The millifluidic chip, fabricated via stereolithography, provided an optimized platform for dual optical and ultrasonic assessments. Results showed strong agreement between the two methods across a range of flow rates, affirming the suitability of the emulsion for velocimetry applications. Furthermore, the acoustic properties of soybean oil droplets support their potential as an echogenic and stable alternative to conventional BMFs. |
| title | Assessing ultrasonic and optical flow velocimetry in a millifluidic device using oil-in-water emulsions as blood mimicking fluid |
| topic | Medical Physics |
| url | https://arxiv.org/abs/2501.16959 |