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| Main Authors: | , , , , |
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| Format: | Preprint |
| Published: |
2025
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| Subjects: | |
| Online Access: | https://arxiv.org/abs/2501.17647 |
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| _version_ | 1866917905737711616 |
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| author | Singhal, Khushank Adamson, Harry Baer, Thomas Salis, Howard Demirel, Melik |
| author_facet | Singhal, Khushank Adamson, Harry Baer, Thomas Salis, Howard Demirel, Melik |
| contents | Gene expression is a complex phenomenon involving numerous interlinked variables, and studying these variables to control expression is essential in bioengineering and biomanufacturing. While cloning techniques for achieving plasmid libraries that cover large design spaces exist, multiplex techniques offering cell culture screening at similar scales are still lacking. We introduced a microcapillary array-based platform aimed at high-throughput, multiplex screening of miniature cell cultures through fluorescent reporters. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2501_17647 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | High Throughput Screening of Expression Constructs using Microcapillary Arrays Singhal, Khushank Adamson, Harry Baer, Thomas Salis, Howard Demirel, Melik Quantitative Methods Biomolecules 00-XX A.0 Gene expression is a complex phenomenon involving numerous interlinked variables, and studying these variables to control expression is essential in bioengineering and biomanufacturing. While cloning techniques for achieving plasmid libraries that cover large design spaces exist, multiplex techniques offering cell culture screening at similar scales are still lacking. We introduced a microcapillary array-based platform aimed at high-throughput, multiplex screening of miniature cell cultures through fluorescent reporters. |
| title | High Throughput Screening of Expression Constructs using Microcapillary Arrays |
| topic | Quantitative Methods Biomolecules 00-XX A.0 |
| url | https://arxiv.org/abs/2501.17647 |