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Main Authors: Mishra, Aayush, Joffe, David, Telidevara, Sankara Surendra, Oakley, David S, Liu, Anqi
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2501.17871
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author Mishra, Aayush
Joffe, David
Telidevara, Sankara Surendra
Oakley, David S
Liu, Anqi
author_facet Mishra, Aayush
Joffe, David
Telidevara, Sankara Surendra
Oakley, David S
Liu, Anqi
contents Recent studies have shown promising results in the detection of Mild Cognitive Impairment (MCI) using easily accessible Electroencephalogram (EEG) data which would help administer early and effective treatment for dementia patients. However, the reliability and practicality of such systems remains unclear. In this work, we investigate the potential limitations and challenges in developing a robust MCI detection method using two contrasting datasets: 1) CAUEEG, collected and annotated by expert neurologists in controlled settings and 2) GENEEG, a new dataset collected and annotated in general practice clinics, a setting where routine MCI diagnoses are typically made. We find that training on small datasets, as is done by most previous works, tends to produce high variance models that make overconfident predictions, and are unreliable in practice. Additionally, distribution shifts between datasets make cross-domain generalization challenging. Finally, we show that MCI detection using EEG may suffer from fundamental limitations because of the overlapping nature of feature distributions with control groups. We call for more effort in high-quality data collection in actionable settings (like general practice clinics) to make progress towards this salient goal of non-invasive MCI detection.
format Preprint
id arxiv_https___arxiv_org_abs_2501_17871
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle On the challenges of detecting MCI using EEG in the wild
Mishra, Aayush
Joffe, David
Telidevara, Sankara Surendra
Oakley, David S
Liu, Anqi
Signal Processing
Machine Learning
Recent studies have shown promising results in the detection of Mild Cognitive Impairment (MCI) using easily accessible Electroencephalogram (EEG) data which would help administer early and effective treatment for dementia patients. However, the reliability and practicality of such systems remains unclear. In this work, we investigate the potential limitations and challenges in developing a robust MCI detection method using two contrasting datasets: 1) CAUEEG, collected and annotated by expert neurologists in controlled settings and 2) GENEEG, a new dataset collected and annotated in general practice clinics, a setting where routine MCI diagnoses are typically made. We find that training on small datasets, as is done by most previous works, tends to produce high variance models that make overconfident predictions, and are unreliable in practice. Additionally, distribution shifts between datasets make cross-domain generalization challenging. Finally, we show that MCI detection using EEG may suffer from fundamental limitations because of the overlapping nature of feature distributions with control groups. We call for more effort in high-quality data collection in actionable settings (like general practice clinics) to make progress towards this salient goal of non-invasive MCI detection.
title On the challenges of detecting MCI using EEG in the wild
topic Signal Processing
Machine Learning
url https://arxiv.org/abs/2501.17871